Echocardiography Examination Of The Cardiac Effects Of Different Regional Anesthesia Methods

Not Applicable

• Conditions: Lumbar Plexus Block; Femur Fracture; Spinal Anesthesia
• Interventions: Device: Transthoracic echocardiogram

• Registration Number: NCT04975386
• Lead Sponsor: Bursa Yüksek İhtisas Education and Research Hospital

Brief Summary

Nerve blocks applied with neuraxial anesthesia and ultrasonography are used for many operations today. Neuraxial blocks cause varying degrees of decrease in the blood pressure level of the patients. Peripheral blocks may be preferred to avoid the cardiac effects of the neuraxial anesthesia method.

Detailed Description

The hypothesis of this study was that spinal anesthesia applied in intertrochanteric femoral fracture operations caused hypotension by lowering the cardiac ejection fraction.

In our study, The investigators aimed to find out the effect of different regional anesthesia methods on the cardiac function of the patients by echocardiography.

Study Timeline

• Status Verified: 2021-07
• Study First Submitted: 2021-07-14
• Study First Submitted QC: 2021-07-22
• Study First Posted: 2021-07-23
• Last Update Submitted: 2021-07-23
• Study Start: 2021-07-29
• Last Update Posted: 2021-07-29
• Primary Completion: 2022-07-29
• Study Completion: 2022-08-15

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

• 60-100 years old
• American Society of Anesthesiologist Score I-IV

Exclusion Criteria

• Local anesthetic allergy
• Bleeding disorder
• Mental disorder
• Allergy to drugs used
• Body mass index above 30

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
lumbar plexus+sacral plexus block	Transthoracic echocardiogram	-
spinal anesthesia	Transthoracic echocardiogram	-

Primary Outcome Measures

Name	Time	Method
Ejection fraction	peroperative	Ejection fraction (EF) measurement will be made with Simpson's method and fractional shortening method.

Secondary Outcome Measures

Name	Time	Method
sedative drug	intraoperative	The drugs used for sedation and their amounts will be recorded.
Entropy	peroperative	Depth of anesthesia will be measured by placing Entropy sensors on the forehead as needed.
cardiac diastolic dysfunction	peroperative	The echocardiogram will measure the flow velocity between the left atrium and ventricle in cm/s in pulsed wave mode and the E/A ratio will be calculated.
intraoperative blood pressure monitoring	peroperative	systolic, diastolic and median blood pressure values
ramsey sedation scale	intraoperative	1. point Awake, restless and/or crying.; 2. points Alert, calm, watching his surroundings.; 3. points Sleepy but responds to verbal stimuli; 4. points Sleepy but immediately responds to glabellar tactile stimuli.; 5. points Sleepy but responds slowly to glabellar tactile stimuli.; 6. points Does not respond to Alerts.