A 12 Week Study to Confirm the Effectiveness of 8mg of Fesoterodine Compared to 4mg of Fesoterodine
- Conditions
- Overactive Bladder
- Interventions
- Registration Number
- NCT01302067
- Lead Sponsor
- Pfizer
- Brief Summary
This study is designed to confirm if 8mg of fesoterodine is more effective in reducing overactive bladder symptoms than 4mg of fesoterodine. In addition the study is designed to assess if the higher dose reduces the overall effect of overactive bladder on the subject's daily life more than the lower dose. The study also assesses the side effects and safety of the two doses.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 2012
- 6 months overactive bladder symptoms, minimum of 2 urgency urinary incontinence episodes per 24 hours and minimum of 8 micturitions per 24 hours.
- Other concurrent and concomitant medication or disease that could put the subjects at additional risk or interfere with the study results.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Placebo Placebo - Fesoterodine 8mg Fesoterodine 8mg - Fesoterodine 4mg Fesoterodine 4mg -
- Primary Outcome Measures
Name Time Method Change From Baseline in Mean Number of Urgency Urinary Incontinence (UUI) Episodes Per 24 Hours at Week 12. Week 12 UUI episodes were defined as those with the Urinary Sensation Scale (USS) rating of 5 in the diary. USS total range 1 to 5: 1. No feeling of urgency, 2. Mild feeling of urgency, 3. Moderate feeling of urgency, 4. Severe feeling of urgency, 5. Unable to hold; leak urine.
- Secondary Outcome Measures
Name Time Method Change From Baseline in Mean Number of Micturitions Per 24 Hours at Week 12. Week 12 Micturitions include episodes of voluntary micturition and episodes of UUI.
Change From Baseline in Mean Number of Micturition-Related Urgency Episodes Per 24 Hours at Week 4. Week 4 The mean number of micturition-related urgency episodes per 24 hours was calculated as the total number of micturitions with USS rating of greater than or equal to (\>=) 3 divided by the total number of days that diary data was collected at that visit. USS total range 1 to 5: 1. No feeling of urgency, 2. Mild feeling of urgency, 3. Moderate feeling of urgency, 4. Severe feeling of urgency, 5. Unable to hold; leak urine.
Change From Baseline in Percentage of Micturition-Related Urgency Episodes Per 24 Hours at Week 12. Week 12 The mean number of micturition-related urgency episodes per 24 hours was calculated as the total number of micturitions with USS rating of greater than or equal to (\>=) 3 divided by the total number of days that diary data was collected at that visit. USS total range 1 to 5: 1. No feeling of urgency, 2. Mild feeling of urgency, 3. Moderate feeling of urgency, 4. Severe feeling of urgency, 5. Unable to hold; leak urine.
Change From Baseline in Health Related Quality of Life (HRQL)-Coping Domain and Total Score of Overactive Bladder Questionnaire (OAB-q) at Week 12. Week 12 OAB-q: self-administered, 33-item, questionnaire, assesses how much participant has been bothered by selected bladder symptoms. Each item rated on Likert scale 1 (not at all) to 6 (a very great deal). Questions 9 to 33 constitute HRQL, includes domains: concern, coping, sleep, and social function. HRQL domain and total raw score derived as sum of scores. Transformed score range 0 to 100 (Total HRQL or domain) = \[(Highest possible raw score-Actual total raw score)/Raw score range\]\*100. Higher transformed scores indicative of better HRQL.
Change From Baseline in Mean Number of Micturitions Per 24 Hours at Week 4. Week 4 Micturitions include episodes of voluntary micturition and episodes of UUI.
Change From Baseline in Percentage of Micturitions Per 24 Hours at Week 4. Week 4 Micturitions include episodes of voluntary micturition and episodes of UUI.
Change From Baseline in Percentage of Micturitions Per 24 Hours at Week 12. Week 12 Micturitions include episodes of voluntary micturition and episodes of UUI.
Change From Baseline in Mean Number of UUI Episodes Per 24 Hours at Week 4. Week 4 UUI episodes were defined as those with the USS rating of 5 in the diary. USS total range 1 to 5: 1. No feeling of urgency, 2. Mild feeling of urgency, 3. Moderate feeling of urgency, 4. Severe feeling of urgency, 5. Unable to hold; leak urine.
Number of Participants With Change From Baseline in Urgency Perception Scale (UPS) at Week 12. Week 12 UPS: single-item, self-administered validated questionnaire. Participant answered: "Which of the following would typically describe your experience when you have a desire to urinate?" on a 3-point scale, 1=usually not able to hold urine; 2=usually able to hold urine (without leaking) until I reach a toilet if I go to the toilet immediately; 3= usually able to finish what I am doing before going to the toilet (without leaking). Change = observation minus baseline. Results categorized as Deterioration (Negative change); no change (Score change=0); improvement (Positive change).
Change From Baseline in Health Related Quality of Life (HRQL)-Concern Domain and Total Score of Overactive Bladder Questionnaire (OAB-q) at Week 12. Week 12 OAB-q: self-administered, 33-item, questionnaire, assesses how much participant has been bothered by selected bladder symptoms. Each item rated on Likert scale 1 (not at all) to 6 (a very great deal). Questions 9 to 33 constitute HRQL, includes domains: concern, coping, sleep, and social function. HRQL domain and total raw score derived as sum of scores. Transformed score range 0 to 100 (Total HRQL or domain) = \[(Highest possible raw score-Actual total raw score)/Raw score range\]\*100. Higher transformed scores indicative of better HRQL.
Change From Baseline in Percentage of UUI Episodes Per 24 Hours at Week 4. Week 4 UUI episodes were defined as those with the USS rating of 5 in the diary. USS total range 1 to 5: 1. No feeling of urgency, 2. Mild feeling of urgency, 3. Moderate feeling of urgency, 4. Severe feeling of urgency, 5. Unable to hold; leak urine.
Change From Baseline in Percentage of UUI Episodes Per 24 Hours at Week 12. Week 12 UUI episodes were defined as those with the USS rating of 5 in the diary. USS total range 1 to 5: 1. No feeling of urgency, 2. Mild feeling of urgency, 3. Moderate feeling of urgency, 4. Severe feeling of urgency, 5. Unable to hold; leak urine.
Number of Participants With Change From Baseline in Patient Perception of Bladder Condition (PPBC) at Week 12. Week 12 PPBC: a self-administered, single-item, questionnaire that asks participants to describe their perception of their bladder-related problems. The PPBC assessment is rated on a 6-point scale: 1=no problems at all, 2=some very minor problems, 3=some minor problems, 4=moderate problems, 5=severe problems, 6=many severe problems. Improvement is defined as negative change from baseline.
Change From Baseline in Health Related Quality of Life (HRQL)-Sleep Domain and Total Score of Overactive Bladder Questionnaire (OAB-q) at Week 12. Week 12 OAB-q: self-administered, 33-item, questionnaire, assesses how much participant has been bothered by selected bladder symptoms. Each item rated on Likert scale 1 (not at all) to 6 (a very great deal). Questions 9 to 33 constitute HRQL, includes domains: concern, coping, sleep, and social function. HRQL domain and total raw score derived as sum of scores. Transformed score range 0 to 100 (Total HRQL or domain) = \[(Highest possible raw score-Actual total raw score)/Raw score range\]\*100. Higher transformed scores indicative of better HRQL.
Change From Baseline in Health Related Quality of Life (HRQL)-Social Interaction Domain and Total Score of Overactive Bladder Questionnaire (OAB-q) at Week 12. Week 12 OAB-q: self-administered, 33-item, questionnaire, assesses how much participant has been bothered by selected bladder symptoms. Each item rated on Likert scale 1 (not at all) to 6 (a very great deal). Questions 9 to 33 constitute HRQL, includes domains: concern, coping, sleep, and social function. HRQL domain and total raw score derived as sum of scores. Transformed score range 0 to 100 (Total HRQL or domain) = \[(Highest possible raw score-Actual total raw score)/Raw score range\]\*100. Higher transformed scores indicative of better HRQL.
Percentage of Participants Who Became Dry at Week 4. Week 4 Percentage of participants with no UUI episode for the three day diary, the numerator being the number of participants with no UUI at a visit and the denominator the total number of participants with UUI\>0 at baseline. UUI episodes defined as those with USS rating of 5 (unable to hold; leak urine) in the diary
Percentage of Participants Who Became Dry at Week 12. Week 12 Percentage of participants with no UUI episode for the three day diary, the numerator being the number of participants with no UUI at a visit and the denominator the total number of participants with UUI \>0 at baseline. UUI episodes defined as those with USS rating of 5 (unable to hold; leak urine) in the diary.
Change From Baseline in Mean Number of Micturition-Related Urgency Episodes Per 24 Hours at Week 12. Week 12 The mean number of micturition-related urgency episodes per 24 hours was calculated as the total number of micturitions with USS rating of greater than or equal to (\>=) 3 divided by the total number of days that diary data was collected at that visit. USS total range 1 to 5: 1. No feeling of urgency, 2. Mild feeling of urgency, 3. Moderate feeling of urgency, 4. Severe feeling of urgency, 5. Unable to hold; leak urine.
Change From Baseline in Percentage of Micturition-Related Urgency Episodes Per 24 Hours at Week 4. Week 4 The mean number of micturition-related urgency episodes per 24 hours was calculated as the total number of micturitions with USS rating of greater than or equal to (\>=) 3 divided by the total number of days that diary data was collected at that visit. USS total range 1 to 5: 1. No feeling of urgency, 2. Mild feeling of urgency, 3. Moderate feeling of urgency, 4. Severe feeling of urgency, 5. Unable to hold; leak urine.
Change From Baseline in Overactive Bladder Questionnaire (OAB-q) Symptom Bother Score at Week 12. Week 12 OAB-q: a self-administered, 33-item, questionnaire that assesses how much the participant has been bothered by selected bladder symptoms. Each item rated by participant on Likert scale 1 (not at all) to 6 (a very great deal). Symptom bother score derived as sum of scores for questions 1-8; lowest possible raw score: 8; highest possible score: 48. Data analyzed based on transformation of the score to a 0 to 100 scale \[(Actual total raw score - lowest possible value of raw score)/range\]\*100. Higher scores values indicative of greater symptom bother.
Change From Baseline in Health Related Quality of Life (HRQL)-Total Score of Overactive Bladder Questionnaire (OAB-q) at Week 12. Week 12 OAB-q: self-administered, 33-item, questionnaire, assesses how much participant has been bothered by selected bladder symptoms. Each item rated on Likert scale 1 (not at all) to 6 (a very great deal). Questions 9 to 33 constitute HRQL, includes domains: concern, coping, sleep, and social function. HRQL domain and total raw score derived as sum of scores. Transformed score range 0 to 100 (Total HRQL or domain) = \[(Highest possible raw score-Actual total raw score)/Raw score range\]\*100. Higher transformed scores indicative of better HRQL.
Trial Locations
- Locations (277)
Women's Healthcare Associates dba Rosemark WomenCare Specialists
🇺🇸Idaho Falls, Idaho, United States
Institute for Female Pelvic Medicine
🇺🇸Allentown, Pennsylvania, United States
Can-Med Clinical Research
🇨🇦Victoria, British Columbia, Canada
Ultra-Med Inc.
🇨🇦Pointe-Claire, Quebec, Canada
South Florida Medical Research
🇺🇸Aventura, Florida, United States
Clinical Innovations, Inc.
🇺🇸Santa Ana, California, United States
Southeastern Research Group, Inc.
🇺🇸Tallahassee, Florida, United States
Broward Research Group
🇺🇸Pembroke Pines, Florida, United States
Center for Women's Research
🇺🇸Chicago, Illinois, United States
Scottsboro Quick Care Clinic
🇺🇸Scottsboro, Alabama, United States
NEA Baptist Women's Clinic
🇺🇸Jonesboro, Arkansas, United States
A Clinic For Women
🇺🇸Little Rock, Arkansas, United States
Medical Affiliated Research Center, Inc.
🇺🇸Huntsville, Alabama, United States
Genova Clinical Research
🇺🇸Tucson, Arizona, United States
James Gordon McMurray, MD
🇺🇸Huntsville, Alabama, United States
Women's Health Specialty Care
🇺🇸Farmington, Connecticut, United States
Sockolov and Sockolov APC
🇺🇸Sacramento, California, United States
PAB Clinical Research
🇺🇸Brandon, Florida, United States
The Office of Dr. Simon Yassear, MD
🇺🇸Carmichael, California, United States
Larry S. Watkins, MD
🇺🇸Little Rock, Arkansas, United States
Uromedix
🇺🇸Aventura, Florida, United States
Lynn Institute of the Ozarks
🇺🇸Little Rock, Arkansas, United States
May Women's Health Clinic
🇺🇸Little Rock, Arkansas, United States
Grossmont Center for Clinical Research
🇺🇸La Mesa, California, United States
Urologic Surgical Center
🇺🇸Charleston, West Virginia, United States
Heartland Research Associates, LLC
🇺🇸Wichita, Kansas, United States
Commonwealth Biomedical Research
🇺🇸Madisonville, Kentucky, United States
Midwest Pharmaceutical Research
🇺🇸St. Peters, Missouri, United States
Independence Family Medicine
🇺🇸Virginia Beach, Virginia, United States
Charleston Internal Medicine, Inc.
🇺🇸Charleston, West Virginia, United States
Seattle Urology Research Center
🇺🇸Burien, Washington, United States
Allegiance Research Specialists
🇺🇸Wauwatosa, Wisconsin, United States
CAMC Physicians Group
🇺🇸Charleston, West Virginia, United States
Hospital Clinico Universidad de Chile
🇨🇱Santiago, RM, Chile
Nzoz "Nasz Lekarz"
🇵🇱Torun, Poland
CHU de Nantes - Hôtel Dieu
🇫🇷Nantes, France
SMO MD GmbH
🇩🇪Magdeburg, Germany
Hôpital CAREMEAU - Service Urologie/Andrologie
🇫🇷Nimes Cedex 9, France
UroLaval
🇨🇦Laval, Quebec, Canada
Jahn Ferenc Del-pesti Korhaz, Urologiai Osztaly
ðŸ‡ðŸ‡ºBudapest, Hungary
CRS Clinical Research Service Moenchengladbach GmbH
🇩🇪Moenchengladbach, Germany
Instituto Medico Especializado (IME)
🇦🇷Buenos Aires, Argentina
Urologicka klinika
🇨🇿Praha 1 - Nove Mesto, Czech Republic
Medi 3 Innlandet
🇳🇴Hamar, Norway
NZOZ Centrum Medyczne
🇵🇱Lodz, Poland
CAMC Clinical Trials Center
🇺🇸Charleston, West Virginia, United States
Toronto Western Hospital, University Health Network
🇨🇦Toronto, Ontario, Canada
Clinical Research Unit
🇿🇦Pretoria, Gauteng, South Africa
Non-governmental Healthcare Institution Departmental Clinical Hospital at Barnaul station OAO RZD
🇷🇺Barnaul, Russian Federation
Urotec
🇨🇦Oshawa, Ontario, Canada
Synexus Clinical Research GmbH
🇩🇪Leipzig, Germany
Nemocnice Jablonec nad Nisou
🇨🇿Jablonec nad Nisou, Czech Republic
Klinische Forschung Dresden GmbH
🇩🇪Dresden, Germany
Centre Hospitalier Universitaire de Sherbrooke
🇨🇦Sherbrooke, Quebec, Canada
Debreceni Egyetem Orvos- es Egeszsegtudomanyi Centrum, Urologiai Klinika
ðŸ‡ðŸ‡ºDebrecen, Hungary
Seoul National University Hospital
🇰🇷Seoul, Korea, Republic of
Al-Azhar University hospital
🇪🇬Cairo, Egypt
Clinical Research Hamburg
🇩🇪Hamburg, Germany
The Catholic University of Korea Seoul St. Mary's Hospital, Department of Urology
🇰🇷Seoul, Korea, Republic of
Herlev Hospital
🇩🇰Herlev, Denmark
Clinica Urologica Centro Trapianti di rene
🇮🇹Foggia, Italy
Urology South Shore Research
🇨🇦Greenfield Park, Quebec, Canada
Allgemeinmedizin Praktische Aerzte
🇩🇪Karlsruhe, Germany
Arztpraxis
🇩🇪Lauenburg, Germany
Praxisklinik Urologie Rhein-Ruhr
🇩🇪Muelheim a.d. Ruhr, Germany
Josa Andras Oktatokorhaz Egeszsegugyi Szolgaltato Nonprofit Kft., Urologiai osztaly
ðŸ‡ðŸ‡ºNyiregyhaza, Hungary
Samsung Medical Center
🇰🇷Seoul, Korea, Republic of
Hôpital Edouard Herriot
🇫🇷Lyon Cedex 03, France
Facharzt fuer Urologie
🇩🇪Reutlingen, Germany
Department of Urology, Korea University Anam Hospital
🇰🇷Seoul, Korea, Republic of
Carema Specialistvard Eslov
🇸🇪Eslov, Sweden
Center for Lakemedelsstudier
🇸🇪Malmo, Sweden
Università Magna Graecia di Catanzaro
🇮🇹Catanzaro, Italy
Klinische Forschung Hannover - Mitte GmbH
🇩🇪Hannover, Germany
Rostov State Medical University, Chair of Urology
🇷🇺Rostov-on-Don, Russian Federation
Klinische Forschung Berlin-Buch GmbH
🇩🇪Berlin, Germany
Klinische Forschung Schwerin GmbH
🇩🇪Schwerin, Germany
City Hospital #4 of Donetsk, Woman Consultative Department
🇺🇦Donetsk, Ukraine
Hagakliniken
🇸🇪Goteborg, Sweden
CTC, Sahlgrenska sjukhuset/SU
🇸🇪Goteborg, Sweden
Klinika Urologii Akademickie Centrum Kliniczne - Szpital Akademii Medycznej w Gdansku
🇵🇱Gdansk, Poland
Vasterviks sjukhus, Kvinnokliniken
🇸🇪Vastervik, Sweden
Clinix Private Clinic
🇿🇦Vosloorus, Gauteng, South Africa
Baillieston Health Centre
🇬🇧Glasgow, United Kingdom
Centrum urologie Povazska Bystrica, s.r.o. urologicka ambulancia
🇸🇰Povazska Bystrica, Slovakia
RMI "Chernivtsi Regional Clinical Hosp.", Dep. of Urology, BSMU, Chair of Surgery and Urology
🇺🇦Chernivtsi, Ukraine
MTPI "Central City Clinical Hospital #1"/Donetsk National Medical University n.a. M. Gorkiy,
🇺🇦Donetsk, Ukraine
Probare
🇸🇪Lund, Sweden
Ladulaas kliniska studier
🇸🇪Skene, Sweden
Verksamhet Urologi
🇸🇪Skovde, Sweden
Royal Hallamshire Hospital
🇬🇧Sheffield, United Kingdom
Mayo Centre
🇿🇦Roodepoort, South Africa
National Taiwan University Hospital, Department of Urology
🇨🇳Taipei, Taiwan
Department of Urology of Donetsk National Medical University at Central City Clinical Hospital #1
🇺🇦Donetsk, Ukraine
Uzhorod City Outpatient Clinic, Prophylaxis Department
🇺🇦Uzhorod, Ukraine
Urology Dept of Zaporizhzhia Medical Academy of Postgraduate Education
🇺🇦Zaporizhzhia, Ukraine
S3 Clinical Research Centers
🇸🇪Vallingby, Sweden
Vinnitsa Regional Clinical Dispensary of Endocrinology
🇺🇦Vinnitsa, Ukraine
Sheepcot Medical Centre
🇬🇧Hertfordshire, United Kingdom
Rapid Medical Research, Inc.
🇺🇸Cleveland, Ohio, United States
Genesis Center for Clinical Research
🇺🇸San Diego, California, United States
San Diego Clinical Trials
🇺🇸San Diego, California, United States
New Horizon Research Center
🇺🇸Miami, Florida, United States
Patient Priority Clinical Sites, LLC
🇺🇸Cincinnati, Ohio, United States
Urology Centers of Alabama
🇺🇸Birmingham, Alabama, United States
Achieve Clinical Research, LLC
🇺🇸Birmingham, Alabama, United States
Dedicated Clinical Research
🇺🇸Phoenix, Arizona, United States
Legacy Clinical Research, LLC
🇺🇸Oklahoma City, Oklahoma, United States
Lynn Health Science Institute
🇺🇸Oklahoma City, Oklahoma, United States
Clinical Trials of Texas, Inc.
🇺🇸San Antonio, Texas, United States
Institute for Women's Health
🇺🇸San Antonio, Texas, United States
Seven Oaks Women's Center
🇺🇸San Antonio, Texas, United States
Roskilde sygehus, Gynaekologisk/obstetrisk afdeling
🇩🇰Roskilde, Denmark
Kvinnokliniken Karolinska Universitetssjukhuset Huddinge
🇸🇪Stockholm, Sweden
Hôpital Tenon - Service d'Urologie
🇫🇷Paris, France
Mobile Ob-Gyn, P.C.
🇺🇸Mobile, Alabama, United States
Genitourinary Surgical Consultants
🇺🇸Denver, Colorado, United States
Urology Associates, PC
🇺🇸Denver, Colorado, United States
Meridien Research
🇺🇸Tampa, Florida, United States
Montgomery Women's Health Associates, P.C.
🇺🇸Montgomery, Alabama, United States
Citrus Valley Medical Research, Inc.
🇺🇸Glendora, California, United States
Diablo Clinical Research, Inc.
🇺🇸Walnut Creek, California, United States
The Women's Clinic of Northern Colorado
🇺🇸Fort Collins, Colorado, United States
Pulmonary Associates of Brandon
🇺🇸Brandon, Florida, United States
Nature Coast Clinical Research
🇺🇸Inverness, Florida, United States
Florida Sleep Disorder Center of Brandon
🇺🇸Brandon, Florida, United States
SJS Clinical Research, Inc.
🇺🇸Destin, Florida, United States
Doctors Medical Center of Walton County
🇺🇸DeFuniak Springs, Florida, United States
Fleming Island Center for Clinical Research
🇺🇸Fleming Island, Florida, United States
Avail Clinical Research, LLC
🇺🇸DeLand, Florida, United States
Altus Research
🇺🇸Lake Worth, Florida, United States
Jacksonville Center for Clinical Research
🇺🇸Jacksonville, Florida, United States
Florida Urology Physicians
🇺🇸Fort Myers, Florida, United States
M & O Clinical Research, LLC
🇺🇸Fort Lauderdale, Florida, United States
OB-GYN Associates of Mid-Florida, PA
🇺🇸Leesburg, Florida, United States
Clinical Research of Central Florida
🇺🇸Winter Haven, Florida, United States
Urology Health Team, PLLC
🇺🇸Ocala, Florida, United States
Advanced OBGYN Associates
🇺🇸West Palm Beach, Florida, United States
Clinical Research Atlanta
🇺🇸Stockbridge, Georgia, United States
North Fulton Urology, PC
🇺🇸Roswell, Georgia, United States
North Georgia Clinical Research
🇺🇸Woodstock, Georgia, United States
North Georgia Internal Medicine
🇺🇸Woodstock, Georgia, United States
Advanced Clinical Research
🇺🇸Meridian, Idaho, United States
Women's Health Practice
🇺🇸Champaign, Illinois, United States
Medical and Surgical Specialists
🇺🇸Galesburg, Illinois, United States
Clinical Investigation Specialists, Inc.
🇺🇸Kenosha, Wisconsin, United States
American Health Network of Indiana, LLC
🇺🇸Greenfield, Indiana, United States
Summit Research Institute
🇺🇸Bloomington, Indiana, United States
MediSphere Medical Research Center, LLC
🇺🇸Evansville, Indiana, United States
Deaconess Clinic Gateway Health Center
🇺🇸Newburgh, Indiana, United States
Health Science Research Center
🇺🇸Pratt, Kansas, United States
Metropolitan Urology
🇺🇸Jeffersonville, Indiana, United States
University of Iowa Healthcare
🇺🇸Iowa City, Iowa, United States
Kentucky Medical Research Center
🇺🇸Lexington, Kentucky, United States
Women's and Family Care dba GTC Research
🇺🇸Shawnee, Kansas, United States
The Office of Dr. Myron I. Murdock, MD, LLC
🇺🇸Greenbelt, Maryland, United States
Central Kentucky Research Associates, Inc.
🇺🇸Mount Sterling, Kentucky, United States
Boston Clinical Trials, Inc.
🇺🇸Boston, Massachusetts, United States
Beacon Clinical Research, LLC
🇺🇸Brockton, Massachusetts, United States
Mount Sterling Clinic
🇺🇸Mount Sterling, Kentucky, United States
Infinity Medical Research
🇺🇸North Dartmouth, Massachusetts, United States
Clinical Research Center of Cape Cod, Inc.
🇺🇸Hyannis, Massachusetts, United States
DM Clinical Research
🇺🇸Springfield, Massachusetts, United States
CRC of Jackson
🇺🇸Jackson, Mississippi, United States
Mississippi Urology Clinic
🇺🇸Jackson, Mississippi, United States
Clinical Research Institute of Michigan, LLC
🇺🇸Chesterfield, Michigan, United States
Mercy Health Research
🇺🇸St. Louis, Missouri, United States
Family Health Care Center
🇺🇸Lincoln, Nebraska, United States
Women's Clinic of Lincoln, P.C.
🇺🇸Lincoln, Nebraska, United States
Lincoln Internal Medicine Associates
🇺🇸Lincoln, Nebraska, United States
Clinical Research Center of Nevada
🇺🇸Las Vegas, Nevada, United States
Premier Research, Inc.
🇺🇸Trenton, New Jersey, United States
Brooklyn Urology Research Group
🇺🇸Brooklyn, New York, United States
Virtua Phoenix Ob-Gyn
🇺🇸Moorestown, New Jersey, United States
United Medical Associates
🇺🇸Binghamton, New York, United States
Premier Medical Group of the Hudson Valley
🇺🇸Poughkeepsie, New York, United States
Mid Hudson Medical Research, PLLC
🇺🇸New Windsor, New York, United States
Urological Surgeons of Long Island
🇺🇸Garden City, New York, United States
Upstate Clinical Research Associates
🇺🇸Williamsville, New York, United States
Kernodle Clinic, Inc.
🇺🇸Burlington, North Carolina, United States
American Health Research
🇺🇸Charlotte, North Carolina, United States
Carolina Urology Partners, PLLC
🇺🇸Concord, North Carolina, United States
Carolina Clinical Trials
🇺🇸Concord, North Carolina, United States
Wake Internal Medicine Consultants, Inc.
🇺🇸Raleigh, North Carolina, United States
University Medical Associates
🇺🇸Huntersville, North Carolina, United States
Carolinas Research Associates
🇺🇸Harrisburg, North Carolina, United States
Wake Research Associates, LLC
🇺🇸Raleigh, North Carolina, United States
Hawthorne Medical Research, Inc.
🇺🇸Winston-Salem, North Carolina, United States
PMG Research of Wilmington, LLC
🇺🇸Wilmington, North Carolina, United States
Hawthorne Medical Research, Inc. - Hawthorne OB/GYN Associates
🇺🇸Winston-Salem, North Carolina, United States
HWC Women's Research Center
🇺🇸Englewood, Ohio, United States
Columbus Clinical Research
🇺🇸Columbus, Ohio, United States
Hometown Urgent Care and Research
🇺🇸Dayton, Ohio, United States
Columbus Center for Women's Health Research
🇺🇸Columbus, Ohio, United States
The Clinical Trial Center, LLC
🇺🇸Jenkintown, Pennsylvania, United States
The Office of Johnny B. Roy, MD
🇺🇸Edmond, Oklahoma, United States
Ohio Clinical Research, LLC
🇺🇸Willoughby Hills, Ohio, United States
Laurel Highlands OB/GYN
🇺🇸Hopwood, Pennsylvania, United States
Richard Kastelic and Associates
🇺🇸Johnstown, Pennsylvania, United States
Clinical Trials Research Services, LLC
🇺🇸Pittsburgh, Pennsylvania, United States
Triangle Urological Group
🇺🇸Pittsburgh, Pennsylvania, United States
Mount Nittany Medical Center Health Services Inc. dba Mount Nittany Physician Group
🇺🇸State College, Pennsylvania, United States
Pish Medical Associates
🇺🇸Uniontown, Pennsylvania, United States
Advanced Clinical Concepts
🇺🇸West Reading, Pennsylvania, United States
Woman's Clinic Ltd.
🇺🇸West Reading, Pennsylvania, United States
Coastal Medical
🇺🇸East Greenwich, Rhode Island, United States
Safe Harbor Clinical Research
🇺🇸East Providence, Rhode Island, United States
Omega Medical Research
🇺🇸Warwick, Rhode Island, United States
Coastal Carolina Research Center
🇺🇸Mt. Pleasant, South Carolina, United States
TLM Medical Services, LLC
🇺🇸Columbia, South Carolina, United States
Southern Urogynecology
🇺🇸West Columbia, South Carolina, United States
PMG Research of Bristol, LLC
🇺🇸Bristol, Tennessee, United States
Internal Medicine and Pediatric Associates of Bristol, PC
🇺🇸Bristol, Tennessee, United States
Adams Patterson Gynocology and Obstetrics, PLLC
🇺🇸Memphis, Tennessee, United States
Heartland Medical PC
🇺🇸New Tazewell, Tennessee, United States
Austin Center for Clinical Research
🇺🇸Austin, Texas, United States
ACRC Trials (Administrative/Mailing Site)
🇺🇸Plano, Texas, United States
Memorial Clinical Associates dba MCA Research
🇺🇸Houston, Texas, United States
North Texas Family Medicine
🇺🇸Plano, Texas, United States
National Clinical Research - Richmond
🇺🇸Richmond, Virginia, United States
Charlottesville Medical Research
🇺🇸Charlottesville, Virginia, United States
Scott and White Healthcare
🇺🇸Temple, Texas, United States
Dean Oregon Clinic
🇺🇸Oregon, Wisconsin, United States
Instituto Urologico Buenos Aires
🇦🇷Buenos Aires, Argentina
Centro de UrologÃa (CDU)
🇦🇷Buenos Aires, Argentina
Office of Dr. Peter Pommerville
🇨🇦Victoria, British Columbia, Canada
Office of Dr. Nazmuddin Merali
🇨🇦Victoria, British Columbia, Canada
Can-Med Clinical Research Incorporated
🇨🇦Victoria, British Columbia, Canada
Queen Elizabeth Health Sciences Centre
🇨🇦Halifax, Nova Scotia, Canada
Office of Dr. Bernard Goldfarb
🇨🇦North Bay, Ontario, Canada
McMaster Institute of Urology, St Joseph's Healthcare Hamilton
🇨🇦Hamilton, Ontario, Canada
Pharos Medical Research Ltd.
🇨🇦Grand Falls-Windsor, Newfoundland and Labrador, Canada
Stanley Flax Medical Professional Corporation
🇨🇦North York, Ontario, Canada
Toronto Urology Clinical Study Group
🇨🇦Toronto, Ontario, Canada
Kouvolan Lääkäriasema
🇫🇮Kouvola, Finland
Saules Seimos Medicinos Centras, JSC
🇱🇹Kaunas, Lithuania
University General Hospital of Larisa/ Urology Department
🇬🇷Larisa, Greece
General Hospital Papageorgiou
🇬🇷Thessaloniki, Greece
Synexus Magyarorszag Kft.
ðŸ‡ðŸ‡ºBudapest, Hungary
Severance Hospital, Yonsei University College of Medicine, Department of Urology
🇰🇷Seoul, Korea, Republic of
Asan Medical Center, Department of Urology
🇰🇷Seoul, Korea, Republic of
Centrum Urologiczne Sp. z o. o.
🇵🇱Myslowice, Poland
Research Institute of Obstetrics and Gynaecology D.O. Otta of North-west Department of RAMS
🇷🇺Saint-Petersburg, Russian Federation
Fakultna nemocnica s poliklinikou Zilina
🇸🇰Zilina, Slovakia
Knowle House Surgery
🇬🇧Plymouth, Devon, United Kingdom
Southern General Hospital
🇬🇧Glasgow, United Kingdom
Cambridge University Hospital Trials NHS Trust
🇬🇧Cambridge, United Kingdom
Ormeau Health Centre
🇬🇧Belfast, Northern Ireland, United Kingdom
Urological Research Network, LLC
🇺🇸Hialeah, Florida, United States
RJE Clinical Research
🇺🇸Dallas, Texas, United States
UROX s.r.o.
🇸🇰Piestany, Slovakia
FN a LFUK Hradec Kralove/Urologicka klinika
🇨🇿Hradec Kralove, Czech Republic
Hospital Lomas de San Luis Internacional
🇲🇽San Luis Potosi, Mexico
Norsk Helseklinikk AS, c/o Heiaklinikken
🇳🇴Lierskogen, Norway
Perpetual Succour Hospital of Cebu Inc.
🇵ðŸ‡Cebu City, Cebu, Philippines
Ruzinovska poliklinika, a.s.
🇸🇰Bratislava, Slovakia
Fakultni nemocnice v Motole
🇨🇿Praha 5, Czech Republic
Forusakutten AS, Avdeling for oppdragsforskning
🇳🇴Stavanger, Norway
Nemocnica s Poliklinikou Svateho Lukasa Galanta
🇸🇰Galanta, Slovakia
Fakultna nemocnica Trencin
🇸🇰Trencin, Slovakia
Chang Gung Medical Foundation. Kaohsiung Chang Gung Memorial Hospital
🇨🇳Kaohsiung, Taiwan
Taipei Veterans General Hospital/Division of Urology
🇨🇳Taipei, Taiwan
Fundacion Centro de Investigacion Clinica CIC
🇨🇴Medellin, Antioquia, Colombia
Dr. Pablo O. Torre Memorial Hospital
🇵ðŸ‡Bacolod City, Philippines
St. Paul's Hospital
🇵ðŸ‡Iloilo City, Philippines
URO CLINIC, s.r.o.
🇸🇰Bratislava, Slovakia
GYNPOR SK, s.r.o. Urogynekologicka ambulancia
🇸🇰Zvolen, Slovakia
Fowey River Practice
🇬🇧Fowey, Cornwall, United Kingdom
Urologicka ambulance
🇨🇿Znojmo, Czech Republic
Androgeos spol. s.r.o.
🇨🇿Praha 6 - Hradcany, Czech Republic
Lääkäriasema Cantti Oy
🇫🇮Kuopio, Finland
Mano Seimos Gydytojas, JSC
🇱🇹Klaipeda, Lithuania
Seimos Gydytojas, JSC
🇱🇹Vilnius, Lithuania
Medi 3 Elverum AS
🇳🇴Elverum, Norway
UROGYN,s.r.o.
🇸🇰Zilina, Slovakia
Clinica Uromed
🇨🇱Santiago, RM, Chile
Solano Y Terront Servicios Medicos Ltda / Unidad Integral de Endocrinologia Uniendo
🇨🇴Bogota, Cundinamarca, Colombia