NCT07548190进行中（未招募）不适用
Bidirectional Cohort Study on Prognostic Model Construction for Acute-on-Chronic Liver Failure
The Second Affiliated Hospital of Chongqing Medical University1 个研究点 分布在 1 个国家目标入组 2,000 人开始时间: 2018年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 2,000
- 试验地点
- 1
- 主要终点
- Primary endpoint was all-cause mortality at days 28, 90, 180, and 360.
研究概览
简要总结
This study constitutes a bidirectional cohort investigation. By collating laboratory parameters and clinical data-including plasma and peripheral blood mononuclear cell (PBMC) analyses-from patients with acute-on-chronic liver failure, it aims to provide a reference framework for predicting prognosis and the occurrence of complications.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of Hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF)
排除标准
- •age < 18 years
- •extrahepatic organ failure unrelated to ACLF
- •active malignancy
- •co-infection with other hepatitis viruses or human immunodeficiency virus (HIV)
- •prior liver transplantation
- •use of immunosuppressants within 6 months before enrollment
- •unclear history of antiviral therapy
结局指标
主要结局
Primary endpoint was all-cause mortality at days 28, 90, 180, and 360.
时间窗: Days 28, 90, 180, and 360
次要结局
未报告次要终点
研究者
研究点 (1)
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