A Functional Architecture of the Brain for Visio

Recruiting

Conditions: stroke cva
10007963

Registration Number: NL-OMON47844

Lead Sponsor: niversiteit van Amsterdam

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 1400

Inclusion Criteria

All participants must meet the following criteria in order to be eligible to
participate in this study:
- Age between 18 and 90 years;
- Dutch speaking., Additional inclusion criteria patient population:
- Stroke patients are eligible if they had ischemic stroke. The diagnosis of
stroke will be made by an experienced neurologist based on the presence of an
acute focal deficit and/or an associated lesion on computed tomography (CT) or
magnetic resonance imaging (MRI);
- Patients with demonstrable or subjective visual impairments due to suspected
brain damage (e.g. tumours, head injury) are also eligible.

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded
from participation in this study:
- History of alcohol or drug abuse;
- Psychiatric disorders which could affect / have affected cognitive function;
- Neurological history (exception: for the patient population a history of
previous stroke is not an exclusion criterion);
- Any other non-neurological disorder influencing cognitive functioning;
- Pre-existent cognitive decline as defined by a score of 3.6 or higher on the
short Informant Questionnaire on Cognitive Decline in the Elderly-IQCODE
Dutch version);
- Pre-existent dependency in activities of daily living., Additional exclusion
criteria patient population:
- Inability to be examined post-stroke due to severe disturbances in
consciousness or inability to comprehend task instructions;
- Contra-indication for MRI scanning.

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Performance on experimental computerised tests of specific visual abilities and<br /><br>associated lesion characteristics.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Performance on post-hoc tests of individual patients who show selective<br /><br>visual impairments to address hypotheses derived from the Goodale & Milner<br /><br>model and contrast them with predictions based on the patchwork model.<br /><br><br /><br>- Performance on neuropsychological tests that tap into different cognitive<br /><br>abilities such as memory or attention. </p><br>