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A clinical study to learn about the effects of a virus that transfers the gene for Glucose- 6-Phosphatase (G6Pase) in adults with Glycogen Storage Disease Type Ia

Phase 1
Conditions
Glycogen storage disease type Ia
MedDRA version: 20.1Level: LLTClassification code: 10056911Term: Glycogen storage disease type IA Class: 10010331
Therapeutic area: Diseases [C] - Nutritional and Metabolic Diseases [C18]
Registration Number
CTIS2023-504004-29-00
Lead Sponsor
ltragenyx Pharmaceutical Inc.
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
12
Inclusion Criteria

Individuals eligible to participate in this study must meet all of the following criteria: 1. Received DTX401 in Study 401GSDIA01, Willing and able to provide written informed consent after the nature of the study has been explained, and prior to any research-related procedures being performed, Willing and able to comply with all scheduled study visits, procedures, and requirements

Exclusion Criteria

Individuals who meet any of the following exclusion criteria will not be eligible to participate in the study: 1. Planned or current participation in any other interventional clinical study that may confound the safety or efficacy evaluation of DTX401 during this study, Presence or history of any condition that, in the view of the Investigator, poses a risk to subject safety or places the subject at high risk of poor compliance or not completing the study or that would significantly affect the interpretation of study results

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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