Early Diagnosis of Malignant Transformation of Pigmentary Skin Lesions

• Conditions: Skin Neoplasm; Malignant Melanoma; Pigmented Nevi

• Registration Number: NCT01167998
• Lead Sponsor: Hadassah Medical Organization

Brief Summary

Malignant Melanoma is a deadly skin cancer that can be cured if diagnosed early. To date atypical pigmented skin lesions are diagnosed by appearance alone and many moles and lesions are excised unnecessarily and on the other hand malignant lesions are missed and diagnosed too late. In this study a protein conjugated to a florescent dye is spread on a suspicious pigmented lesion, the hypothesis is that this protein binds to malignant cells only and thus with a special camera that picks up the dye we can find pigmented lesions with early malignant transformation.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-07
• Study First Submitted: 2010-07-21
• Study First Submitted QC: 2010-07-21
• Study First Posted: 2010-07-22
• Status Verified: 2017-02
• Primary Completion: 2017-12
• Last Update Submitted: 2018-08-01
• Last Update Posted: 2018-08-02
• Study Completion: 2019-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• pigmented lesion indicated for surgical excision
• over 18 years of age

Exclusion Criteria

• pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

: Hadassah Medical Organization,; 🇮🇱 Jerusalem, Israel