JPRN-UMIN000028030已完成未知
The prediction using diffusion-weighted MRI of the response evaluation in unresectable pancreatic cancer in patients undergoing neoadjuvant therapy. A pilot study - the response evaluation in unresectable pancreatic cancer in patients undergoing neoadjuvant therapy. A pilot study
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 28
研究概览
简要总结
Pre/post-treatment whole tumor ADC value correlated with tumor cell destruction rate among all parameters (R=0.630/0.714, P<0.001/<0.0001). The post-treatment cutoff value of vascular abut site ADC for discriminating between grade<IIb and >=grade IIb was determined as 1.42x10-3 mm2/s and predicts R0 curability. For histological response, the post-treatment whole tumor ADC cutoff value for discriminating between grade<IIb and >= grade IIb was determined as 1.40x10-3 mm2/s.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 20years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1. Without severe drug allergy. 2. With history of malignant disease within 5 years. 3. Active stutus of infectious disease. 4. With metal in body which is contraindication for MRI. 5. With claustrophobia. 6. Incapability to collaborate in respiration. 7. The presence of uncontrollable ascites. 8. The presence of uncontrollable DM 9. The presence of uncontrollable CHD, angina, HTN, and arrhythmia. 10. The presence of severe neurological, psychological disease or their history.
研究者
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