NCT00215280已完成不适用
Studies on the Epidemiology and Control of Mansonella Perstans Infection in Uganda
DBL -Institute for Health Research and Development1 个研究点 分布在 1 个国家目标入组 1,000 人开始时间: 2005年11月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- microfilariae periodicity patterns
研究概览
简要总结
Mansonella perstans (M. perstans) infection is widespread in Uganda. Knowledge about the epidemiology of this infection, and of the morbidity it induces is poor, and no effective treatment is available. The study aims at providing data on diagnostic, epidemiological, morbidity and treatment aspects of M. perstans infections in Uganda.
详细描述
Overall objective: to investigate diagnostic, epidemiological and treatment aspects of M. perstans in Uganda with relevance to control
Specific objectives:
- To establish the pattern of diurnal periodicity of M. perstans microfilaraemia in humans
- To establish the patterns of M. perstans microfilaraemia and possible clinical manifestations related to this infection in two communities with medium to high endemicity
- To determine the efficacy of ivermectin alone and the combination of ivermectin and albendazole on M. perstans microfilaraemia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 5 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Individuals >= 5 years with or without M. perstans infection
排除标准
- •Individuals < 5 years
- •Pregnant women
结局指标
主要结局
microfilariae periodicity patterns
epidemiology of M. perstans at community level
clinical spectre among infected
reduction in microfilaraemia
次要结局
- treatment effect on clinical manifestations
研究者
研究点 (1)
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