Application of Intrahepatic Arterial Infusion Chemotherapy for Patients With High Risk of Liver Metastases After Pancreatic Cancer Surgery
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Death
研究概览
简要总结
Clinical results on intra-arterial adjuvant chemotherapy for prevention
of liver metastasis following curative resection of pancreatic cancer
详细描述
In this study, the investigator try to select 80 patients who received radical surgery for pancreatic cancer, whose circulating tumor cells(CTCs) count then performed on intraoperative portal venous blood to predict postoperative liver metastasis and were divided into two groups. for those who have high CTCs count may have more chance for the occurrence of postoperative liver metastasis was applied hepatic arterial perfusion chemotherapy with minimal dynamic randomization. The aim is to evaluate the feasibility of hepatic arterial infusion chemotherapy for the prevention of postoperative liver metastasis and improvement of prognosis of pancreatic cancer, so as to further improve postoperative management of pancreatic cancer
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
盲法说明
Pancreatic cancer patients who received chemotherapy through peripheral vein after operation
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •pancreatic cancer patients who received the radical operation
排除标准
- •who accepted chemotherapy before operation or who cannot or do not will to accepted enrolled into this study
研究组 & 干预措施
Intrahepatic Arterial Infusion chemotherapy
chemotherapy through intrahepatic arterial Infusion is one of the most widely used liver tumor treatments.
干预措施: Intrahepatic Arterial Infusion (Device)
control
chemotherapy through Peripheral venous is one of the regularly used method.
结局指标
主要结局
Death
时间窗: up to 12 months
Overall survival time after operation
次要结局
未报告次要终点