The Effect of topical lipogel containing herbal extracts of Ziziphus jujuba and Echium amoenum on pruritus severity in hemodialysis patient

Phase 3

• Conditions: Pruritus in hemodialysis patients.; Pruritus, unspecified; L29.9

• Registration Number: IRCT20110906007494N33
• Lead Sponsor: Mazandaran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 6 October 2020

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Hemodialysis patients aged 18 years and older
End-stage renal disease undergoing regular dialysis treatment at least two or three times a week for six months
Having itching in the last two weeks and having an itching intensity score using the Usipovich Itching Intensity Scale (ISS) in the range of severe and moderate pruritus
Full alertness and ability to communicate
Parathyroid hormone (PTH), <300
Phosphor(P) <6

Exclusion Criteria

Existence of wounds in the limbs
Generalized limb edema (more than one plus (+1)
Pregnancy
Breastfeeding
Other chronic diseases and cancer
Taking other topical medications and antihistamines
History of any allergies (skin, especially to plant compounds)

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pruritus. Timepoint: The first visit; the first, second, third and fourth weeks after starting to use lipogels. Method of measurement: Itching 48-point scale.