EUCTR2013-003413-18-NL进行中（未招募）1 期
Arthritis Prevention In the Pre-clinical Phase of RA with Abatacept. - APIPPRA
eiden University Medical Center0 个研究点目标入组 206 人开始时间: 2015年9月28日最近更新:
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 206
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •- Male or female subjects, aged = 18 years.
- •- Arthralgia that is considered to be inflammatory in nature.
- •- ACPA and RF positive, or high titre ACPA.
- •- Able and willing to give written informed consent and comply with the requirements of the study protocol.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 206
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 206
排除标准
- •- Clinically apparent arthritis, as assessed by a rheumatologist.
- •- A history of inflammatory arthritis, as assessed by a rheumatologist.
- •- History or current use of DMARDs or biologics.
- •- History of oral or parenteral use of corticosteroids within the last 12 weeks.
- •- Co-morbidities requiring treatment with immunosuppressive or immune modulating therapy.
- •- Chronic illnesses that would, in the opinion of the investigator, put the subject at risk.
- •- Recipients of a live vaccine within 4 weeks of inclusion.
- •- Pregnant or breastfeeding
- •- Unable to give informed consent
研究者
相似试验
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Arthritis Prevention In the Pre-clinical Phase of RA with Abatacept.gewrichsaandoeningenArthralgiaReumatoid Arthritis10003816NL-OMON47610eids Universitair Medisch Centrum20
进行中（未招募）
1 期
Arthritis prevention with abataceptThe target population for therapeutic intervention will be subjects who carry serum autoantibodies (antibodies to citrullinated protein antigens – ACPArheumatoid factor – RF) and who have joint pains (arthralgia) but no joint swelling. These subjects are deemed to be at highest risk of developing rheumatoid arthritis.MedDRA version: 20.0 Level: PT Classification code 10003239 Term: Arthralgia System Organ Class: 10028395 - Musculoskeletal and connective tissue disordersEUCTR2013-003413-18-GBKing’s College London206
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