Transition From Acute to Chronic Pain After Inguinal Hernia, Hysterectomy and Thoracotomy: Analysis of Risk Factors and Association With Genetic Polymorphisms

Completed

• Conditions: Chronic Postoperative Pain
• Interventions: Procedure: Thoracotomy .; Procedure: Hysterectomy.; Procedure: Inguinal herniorraphy.

• Registration Number: NCT01510496
• Lead Sponsor: Fundacion IMIM

Brief Summary

The treatment of postoperative pain continues to be inadequate in the investigators practice setting.

Inadequate pain treatment not only contributes to postoperative complications in the short term but can also be a factor that favors the development of chronic postoperative pain and diminishes long-term quality of life. Risk factors that can lead to a transition to chronic pain need to be analyzed.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-01
• Study First Submitted: 2011-12-23
• Study First Submitted QC: 2012-01-11
• Study First Posted: 2012-01-16
• Primary Completion: 2012-12
• Study Completion: 2014-07
• Status Verified: 2015-12
• Last Update Submitted: 2015-12-29
• Last Update Posted: 2015-12-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 3979

Inclusion Criteria

• Patients with given inform consent, aged mor than 18 years, who undergo scheduled surgery of one of the following types: inguinal hernia (men), hysterectomy, thoracotomy (men).

Exclusion Criteria

• Patients aged less than 18 years,
• Patients requiring reoperation because of surgical complications.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients who had thoracotomy.	Thoracotomy .	-
Patients who had hysterectomy.	Hysterectomy.	-
Patients who had inguinal herniorraphy.	Inguinal herniorraphy.	-

Primary Outcome Measures

Name	Time	Method
Evaluation of chronic postsurgical pain.	After 3 and 12 months of surgery.	After 3 months a physical examination will take place and after 12 months a follow-up will be reported by phone.

Secondary Outcome Measures

Name	Time	Method
Predictive factors of chronic postsurgical pain.	After 3 and 12 months of surgery.	Preoperative (psychological factors, preoperative pain, pharmacologic treatment) intraoperative (surgical technic, type of anaestesia) and postoperative(posoperative pain, surgical complications and treatment of postoperative pain).

Trial Locations

Locations (26)

Hospital Universitari de Bellvitge; 🇪🇸 L'Hospitalet de Llobregat, Barcelona, Spain

Hospital Municipal de Badalona; 🇪🇸 Badalona, Barcelona, Spain

Hospital Universitari Germans Trias i Pujol; 🇪🇸 Badalona, Barcelona, Spain

Hospital de Santa Caterina; 🇪🇸 Salt, Girona, Spain

Hospital de Mataro; 🇪🇸 Mataro, Barcelona, Spain

Hospital de Granollers; 🇪🇸 Granollers, Barcelona, Spain

Hospital de Viladecans; 🇪🇸 Viladecans, Barcelona, Spain

Hospital de San Bernabé; 🇪🇸 Berga, Barcelona, Spain

Hospital del Mar; 🇪🇸 Barcelona, Spain

Hospital Parc Tauli; 🇪🇸 Sabadell, Barcelona, Spain

Hospital Mutua de Terrassa; 🇪🇸 Terrassa, Barcelona, Spain

Hospital General de Manresa; 🇪🇸 Manresa, Barcelona, Spain

Hospital Universitari Doctor Josep Trueta de Girona; 🇪🇸 Girona, Spain

Hospital de la Santa Creu i Sant Pau; 🇪🇸 Barcelona, Spain

Hospital Universitari Mutua de Terrassa; 🇪🇸 Terrassa, Barcelona, Spain

Hospital General Universitario de Valencia; 🇪🇸 Valencia, Spain

Hospital Clínic i Provincial de Barcelona; 🇪🇸 Barcelona, Spain

Hospital Sant Joan de Reus; 🇪🇸 Reus, Tarragona, Spain

Hospital Universitari de la Fe; 🇪🇸 Valencia, Spain

Hospital del Sant Boi; 🇪🇸 Barcelona, Spain

Hospital de l'Esperança; 🇪🇸 Barcelona, Spain

Hospital Lluís Alcanyís de Xàtiva; 🇪🇸 Xàtiva, València, Spain

Hospital Universitari Vall d'Hebron; 🇪🇸 Barcelona, Spain

Hospital Sagrat Cor; 🇪🇸 Barcelona, Spain

Hospital Santa Maria; 🇪🇸 Lleida, Spain

Hospital Clínico de Valencia; 🇪🇸 Valencia, Spain