JPRN-UMIN000018283已完成未知
HLA-mismatched allogeneic hematopoietic stem cell transplantation for standard-risk advanced hematological disease using low-dose alemtuzumab - HLA-mismatched HSCT for standard-risk hematological disease using low-dose alemtuzumab
Division of Hematology, Saitama Medical Center, Jichi Medical University0 个研究点目标入组 12 人开始时间: 2015年7月13日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 12
研究概览
简要总结
The primary outcome measure of this study was DFS at 1 year, but it was below 50%, which was DFS at 1 year in the previous study using alemtuzumab. In this study, MDS with complex karyotype was included as a standard risk, and such patients relapsed. Risk stratification should be reconsidered. NRM was in an acceptable range. The improvements to decrease the RR are needed, such as the reduction of methotrexate dose based on the protocol which had used in high-risk patients.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 16years-old 至 70years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1.Patients with poorly controlled active infection. 2.Patients with coexistence of malignancy. 3.Patients who are pregnant or nursing. 4.Patients with serious mental disorder. 5.Patients with HIV antibody positive. 6.Patients who are allergic to drugs used in conditioning regimen or GVHD prophylaxis.
研究者
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