Efficacy of Morning-only Bowel Preparation for Afternoon Colonoscopy.
- Conditions
- Colon Cancer
- Interventions
- Drug: Polyethylene Glycol afternoonDrug: Polyethylene Glycol morning
- Registration Number
- NCT00687830
- Lead Sponsor
- Cleveland Clinic Florida
- Brief Summary
The study aims to study the adequacy of bowel preparation (colon cleansing) for afternoon colonoscopies. The conventional regimen of giving bowel prep on the evening prior to the day of the colonoscopy will be compared with that given on the morning of an afternoon colonoscopy. Endoscopist scoring the bowel cleansing efficacy with an Ottawa Scale are blinded to the randomization process.
- Detailed Description
Two bowel preparation regimens of Polyethylene Glycol (PEG), commonly referred to as "Golytely" will be tested for their efficacy (bowel cleansing effect) and patient tolerability. The goal is to reduce the failure rates of afternoon colonoscopies, for which, one of the main reasons attributed is inadequate bowel preparation. For the afternoon colonoscopies, the conventional PEG regimen given on the evening prior to the day of the colonoscopy will be compared with the novel PEG regimen given on the morning of the day of the colonoscopy. The comparison will be drawn for two measures - bowel cleansing effect measured from the questionnaire given to the gastroenterologists performing the colonoscopy and the patient tolerability evaluated from the information gathered from the patient's questionnaire.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 136
- All patients attending the GI Clinic at CCF who are prescribed colonoscopy and are willing to get the procedure done in the afternoon.
- Colonoscopy is contraindicated
- Prior Colectomy or colon surgery.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Polythylene Glycol (PEG) in the evening Polyethylene Glycol afternoon Bowel preparation with Polyethylene Glycol given in the evening prior to the day of the afternoon colonoscopy. 'Polyethylene Glycol afternoon' Polythylene Glycol (PEG) in the Morning Polyethylene Glycol morning Bowel preparation with Polyethylene Glycol given on the morning of the day of the afternoon colonoscopy. 'Polyethylene Glycol morning'
- Primary Outcome Measures
Name Time Method Comparing All Morning Bowel Prep to Evening Bowel Prep for Patients Undergoing Afternoon Colonoscopies. (Using Ottawa Scale Scores, Range 0-14) Lower Score Indicates a Better Outcome. Within 1 hr after the colonoscopy procedure
- Secondary Outcome Measures
Name Time Method Patient Satisfaction in the Two Groups, All Morning Prep vs. All Evening Bowel Prep. An hour before the colonoscopy procedure Variable used to assess patient satisfaction: Loss of sleep. The numbers below depict the number of participants who experienced loss of sleep.
Trial Locations
- Locations (1)
Cleveland Clinic Florida
🇺🇸Weston, Florida, United States