Continuous Positive Air Way Pressure in Cardiac Rehabilitation After CABG

Not Applicable

Completed

• Conditions: Post-cardiac Surgery
• Interventions: Other: Continuous Positive Air Way Group; Other: Control Group

• Registration Number: NCT05044559
• Lead Sponsor: Riphah International University

Brief Summary

Different studies reported that CPAP is effective to prevent respiratory complication in post CABG patient and have greater impact on walking time, ventilatory function and breathing pattern.

Detailed Description

The walking time (6 minute walk test), effect on arterial blood gasses and long term effects of CPAP on cardiac activity, the previous studies focus only on the acute effects of CPAP along with specific exercises but did not tell about the long term effects. based on these finding this study is design to assess the effectiveness of CPAP in Post-op CABG patients regarding there early mobilization, walking time, ABGs and Ejection Fraction as there prognostic parameters in both phase-1 cardiac rehabilitation within hospital as well as in long-term prognosis, is of great interest.

Study Timeline

• Study Start: 2019-07-15
• Primary Completion: 2020-02-27
• Study Completion: 2020-02-27
• Status Verified: 2021-09
• Study First Submitted: 2021-09-13
• Study First Submitted QC: 2021-09-13
• Study First Posted: 2021-09-14
• Last Update Submitted: 2021-09-14
• Last Update Posted: 2021-09-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 38

Inclusion Criteria

• age between 35 to 60 years.
• With a clinical diagnosis of coronary artery disease, underwent elective CABG (Acute)

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Exclusion Criteria

• Low ejection friction (15%)
• Patient those who have any arrhythmias
• Unstable angina
• Patient having pace maker and implantable cardioverter defibrillator
• COPD and asthmatic patient
• Patient having BMI more then 40

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Continuous Positive Air Way Group	Continuous Positive Air Way Group	Day 1: Use of CPAP between 10 and 12 cmH2O according to tolerance for 20 minutes two time a day at first day of post surgery bed mobility chest physiotherapy ,active assistive ROM 5 repetitions of upper and lower limb, ACBT cycle. ABGS was analyses at first minute of exercise. and vital was record after exercise. Day 2: Active ROM exercise progress of 5 repetitions bed to chair mobility. same exercise progress with 5 repetition and 5 minute walk( day 3rd ).walking time was increase with 10 min at 4 day and at 5th day stair climbing the ABGS was record in ICU 3 days.
Control Group	Control Group	Day 1: Bed mobility chest physiotherapy, active assistive ROM 5 repetitions of upper and lower limb, ACBT cycle. ABGS was analyses at first minute of exercise and vital was record after exercise. Day 2: Active range of motion exercise progress with 5 repetitions bed to chair mobility. same exercise progress with 5 repetition and 5 minute walk( day 3rd ).walking time will increase with 10 min at 4 day and at 5th day stair climbing the ABGS was record in ICU 3 days.

Primary Outcome Measures

Name	Time	Method
Arterial Blood Gasses	3 days	measures oxygen and carbon dioxide levels in your blood. It also measures your body's acid-base (pH) level, which is normally balanced when you are healthy.

Secondary Outcome Measures

Name	Time	Method
6 minute walk test	3 days	gold standard test to measure exercise capacity and requires less physical space and allows for easier monitoring of vital parameters
Ejection Fraction	4 week	expressed as a percentage, of how much blood the left ventricle pumps out with each contraction.
Short Form 12 Questionnaire	4 weeks	measuring tool for mental and physical health components. It consists of 12 questions which cover the eight health domain with one or two question per domain

Trial Locations

Locations (1)

Northwest General Hospital and research center; 🇵🇰 Peshawar, KPK, Pakistan