A ?omparison of the different regional anesthesia methods efficacy in chronic pain syndrom prevention in lung cancer surgery
Not Applicable
Completed
- Registration Number
- ISRCTN12472990
- Lead Sponsor
- P.A. Herzen Moscow Cancer Research Institute
- Brief Summary
2018 Results article in https://pubmed.ncbi.nlm.nih.gov/29925724/ (added 17/03/2023)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
All consecutive patients scheduled for thoracotomy were screened for study inclusion using the following eligibility criteria: adult patients and ASA physical status from I to III.
Exclusion Criteria
1. General anesthesia within 7 days before study inclusion
2. Administration of experimental drug within 30 days before surgery
3. Preoperative chronic postoperative pain syndrome
4. Acute unstable angina
5. Acute myocardial infarction documented by laboratory findings in the past 6 weeks
6. Heart rate (HR) < 50 beats per min (bpm)
7. Systolic blood pressure (SBP) < 100 mmHg
8. Heart block
9. Pre-operative vasopressor administration
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> 1. Frequency and intensity of the CPTPS is measured using the Visual Analogue Scale (0 = no pain and 100 mm = worst possible pain) at 6 months after surgery<br> 2. Effectiveness of TEA, PVB, and INB in CPTPS prevention are measured using the Visual Analogue Scale (0 = no pain and 100 mm = worst possible pain) at 6 months after surgery<br>
- Secondary Outcome Measures
Name Time Method <br> 1. Intensity of APTPS and CPTPS between groups are measured using the Visual Analogue Scale (0 = no pain and 100 mm = worst possible pain) at 7 days, 1 and 6 months after surgery.<br> 2. Pain is measured using the Visual Analogue Scale (0 = no pain and 100 mm = worst possible pain) at 7 days, 1 and 6 months after surgery<br>