Corneal Changes After Crosslinking in Keratoconus Patients Compared to the Untreated Fellow Eye
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- Change in maximum keratometry (Kmax) as measured by the Pentacam HR
研究概览
简要总结
The purpose of this retrospective study is to assess corneal changes (keratometry, pachymetry) and change in visual acuity (VA) in keratoconus patients after unilateral crosslinking treatment compared to the untreated fellow eye. The corneal measurements obtained preoperatively and 2 to 14 months postoperatively using a Pentacam rotating scheimpflug camera are analyzed. Furthermore, pre-existing or actual ocular pathology or/and ocular surgeries as potential factors involved in treatment outcome are also evaluated.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Keratoconus patients after unilateral crosslinking treatment
排除标准
- •Morphological changes of the cornea caused be ocular infection or trauma (e.g. corneal scarring)
- •Other pre-existing corneal surgery (e.g. corneal transplantation, implantation of intrastromal corneal ring segments)
结局指标
主要结局
Change in maximum keratometry (Kmax) as measured by the Pentacam HR
时间窗: after completion of data collection based on the measurements preoperatively and 2-14 months postoperative
次要结局
- Change in corneal thickness as measured by the Pentacam HR(retrospective analysis from preoperatively to 2-14 months postoperatively)
- Change in visual acuity (VA)(retrospective analysis from preoperatively to 2-14 months postoperatively)
- Evaluation of pre-existing ocular pathology or/and ocular surgery as potential factors involved in treatment outcome(retrospective analysis from preoperatively to 2-14 months postoperatively)
研究者
Prof. Dr. med. Mike P. Holzer
Ophthalmologist, FEBO
Heidelberg University