Corneal Changes After Crosslinking in Keratoconus Patients Compared to the Untreated Fellow Eye
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Keratoconus
- Sponsor
- Heidelberg University
- Enrollment
- 66
- Locations
- 1
- Primary Endpoint
- Change in maximum keratometry (Kmax) as measured by the Pentacam HR
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
The purpose of this retrospective study is to assess corneal changes (keratometry, pachymetry) and change in visual acuity (VA) in keratoconus patients after unilateral crosslinking treatment compared to the untreated fellow eye. The corneal measurements obtained preoperatively and 2 to 14 months postoperatively using a Pentacam rotating scheimpflug camera are analyzed. Furthermore, pre-existing or actual ocular pathology or/and ocular surgeries as potential factors involved in treatment outcome are also evaluated.
Investigators
Prof. Dr. med. Mike P. Holzer
Ophthalmologist, FEBO
Heidelberg University
Eligibility Criteria
Inclusion Criteria
- •Keratoconus patients after unilateral crosslinking treatment
Exclusion Criteria
- •Morphological changes of the cornea caused be ocular infection or trauma (e.g. corneal scarring)
- •Other pre-existing corneal surgery (e.g. corneal transplantation, implantation of intrastromal corneal ring segments)
Outcomes
Primary Outcomes
Change in maximum keratometry (Kmax) as measured by the Pentacam HR
Time Frame: after completion of data collection based on the measurements preoperatively and 2-14 months postoperative
Secondary Outcomes
- Change in corneal thickness as measured by the Pentacam HR(retrospective analysis from preoperatively to 2-14 months postoperatively)
- Change in visual acuity (VA)(retrospective analysis from preoperatively to 2-14 months postoperatively)
- Evaluation of pre-existing ocular pathology or/and ocular surgery as potential factors involved in treatment outcome(retrospective analysis from preoperatively to 2-14 months postoperatively)