DRKS00006057招募中不适用
Evidence and functions of surfactant-associated proteins and trefoil factor family (TFF) peptides in the synovial fluid, synovial membrane and cartilage tissue in children and adolescents with inflammatory joint diseases - TFF-Surfactant-JIA-2013
Dekanat der MLU Halle-Wittenberg0 个研究点目标入组 135 人开始时间: 2014年7月4日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 135
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 1 Days 至 16 Years（—）
- 性别
- All
入选标准
- •Gender: Both, male and female
- •Minimum age: 1 day
- •Maximum age: 16 years
- •Additional Inclusion Criteria
- •1. Confirmed JIA (according to ILAR 1997)
- •2. Age = 1 day up to = 16 years for patients with JIA and joint infections
- •3. Age for autopsy cases (non-JIA): premature babies up to 16 years of age
- •4. In the case of JIA and non-synovectomy cases”: New manifestation of JIA and/or prior to use of immunomodulation (corticoids, MTX, other basic medications, biologicals)
- •5. Collection of a blood sample, puncture of the joint, arthroscopic synovectomies, open synovectomies or chondrectomies for a medical indication (e.g. JIA or joint infection)
- •6. Infections of joints before antibiotic treatment
- •7. Authorised autopsies for deceased children and adolescents
排除标准
- •1. Patients with JIA that belong to none or 2 subtypes of JIA
- •2. Any infection in the autopsy group
- •3. Any infection in the JIA group
- •4. Any infection in the synovectomy group
- •5. Lack of medical indication to collect blood samples, arthrocenteses, synovectomies, chondrectomies or procedures on the joint in general
- •6. Patients who have already commenced immunosuppression or immunomodulation in the JIA group (non-synovectomies)
- •7. Procedures on the jaw joint
- •8. Suspected shaken baby syndrome in the autopsy groups
- •9. Lack of written consent forms of the parents and/or patients to any medically indicated joint procedures or to collect blood samples
- •10. Lack of written informed consent forms of the parents/guardians in the cases of clinical post mortem examinations (autopsy cases)
- •11. Lack of written consent of the public prosecution office in exceptional cases involving court-ordered post mortem examinations
研究者
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