Social Effects of Alcohol
试验速览
- 阶段
- 早期 1 期
- 状态
- 已完成
- 入组人数
- 37
- 试验地点
- 1
- 主要终点
- self-reported feelings of connection
研究概览
简要总结
In this study the investigator will assess the effect of a moderate dose of alcohol on emotional responses and feelings of connection during a dyadic semi-structured social interaction
详细描述
The study will use a within-subject crossover design with four sessions, in which participants receive alcohol or placebo across sessions. During the four sessions, the participants will engage in a conversation with a stranger, and emotional responses and feelings of connection will be assessed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 21 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •non-problem alcohol consumption of 2-20 drinks per week
- •high school diploma or equivalent
- •BMI between 19 and 26
- •verbal fluency in English
排除标准
- •High blood pressure
- •Any medical condition requiring regular medication
- •Individuals with a current (within the last year) DSM-IV Axis 1 diagnosis
- •Women who are pregnant or trying to become pregnant.
研究组 & 干预措施
Alcohol-alcohol
Both conversation partners receive alcohol
干预措施: Alcohol (Drug)
placebo-placebo
Both conversation partners receive placebo
干预措施: Placebo (Drug)
alcohol-placebo
participant receives alcohol and conversation partner receives placebo
干预措施: Alcohol (Drug)
placebo-alcohol
participant receives placebo and conversation partner receives alcohol
干预措施: Placebo (Drug)
结局指标
主要结局
self-reported feelings of connection
时间窗: at the end of each session (3.5 hrs post-drug administration). Changes across sessions will be assessed
self-other overlap measure ratings 1-7, greater ratings indicates greater feelings of connection
facial emotional responses
时间窗: during the length of the conversation (45 min)
alterations in the rate of positive facial expressions during the conversation, measured by muscle action units. These will be compared between the drug and placebo sessions
次要结局
未报告次要终点