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Clinical Trials/NCT06701890
NCT06701890
Recruiting
N/A

Observational Study of Travellers Pathologies

Institut Pasteur1 site in 1 country11,000 target enrollmentDecember 9, 2024

Overview

Phase
N/A
Intervention
Not specified
Conditions
Travel-Related Illness
Sponsor
Institut Pasteur
Enrollment
11000
Locations
1
Primary Endpoint
Determine the incidence of pathologies occurring during a travel outside the metropolitan territory.
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

Traveling to emerging countries is associated with a significant risk of encountering health issues specific to the destination, such as gastrointestinal and respiratory infections, malaria episodes, and road traffic accidents.These conditions are associated with behavioral, geographical, or environmental risk factors. A better understanding of these factors will enable the development of targeted recommendations to minimize travel related health issues.

The main objective of this study is to determine the incidence of pathologies occurring during travel outside the metropolitan territory.

Detailed Description

Traveling to emerging countries is associated with a significant risk of encountering health issues specific to the destination, such as gastrointestinal and respiratory infections, malaria episodes, and road traffic accidents.These conditions are associated with behavioral, geographical, or environmental risk factors. A better understanding of these factors will enable the development of targeted recommendations to minimize travel related health issues. The main objective of this study is to determine the incidence of pathologies occurring during travel outside the metropolitan territory. Furthermore, two key aspects from a Public Health perspective are associated with travel and the globalization of exchanges: the acquisition of emerging pathogens or pathogens with antimicrobial resistance of concern. To study these two aspects, the EOP study includes two sub-studies called EOP-Arbo and EOP-AMR. * EOP-Arbo : The objective of this sub-study is to determine the risk of contracting an arboviral disease during travel, as well as the factors that may favor infection. For this, blood samples will be collected. * EOP-AMR : The objective of this sub-study is to determine the risk of contracting an antibiotic-resistant bacteria during the trip. For this, faecal samples will be collected.

Registry
clinicaltrials.gov
Start Date
December 9, 2024
End Date
December 2036
Last Updated
last year
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • For all participants in the EOP study :
  • Travel duration ≤ 3 days
  • Travel duration \> 12 months
  • Person traveling as part of an expatriation without planned movement outside the settlement in the destination country
  • Person under legal protection or unable to express consent for participation
  • For the EOP-Arbo Sub-study :
  • Individuals deemed clinically and/or biologically unfit by the investigator to undergo the blood samples required for the study.
  • For the EOP-AMR Sub-study :
  • No specific exclusion criteria.

Outcomes

Primary Outcomes

Determine the incidence of pathologies occurring during a travel outside the metropolitan territory.

Time Frame: 10 years

Number of subjects who developed a pathology during the travel among participants

Secondary Outcomes

  • For EOP-Arbo sub-study : Determine the prevalence for the occurrence of an arboviral disease (dengue, chikungunya, Zika) during the travel.(10 years)
  • For EOP-AMR sub-study : Determine the prevalence for the acquisition of multi-resistant bacteria (MRB) during the travel.(10 years)

Study Sites (1)

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