Physiological Effects of High-Flow Tracheal Oxygen Via An Modified Interface in Tracheostomized Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Tracheostomy
- Sponsor
- Capital Medical University
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- The mean end expiratory pressure.
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
Tracheostomy is often performed in patients after or anticipated prolonged mechanical ventilation, who are usually required oxygen therapy after discontinuation of mechanical ventilation.
Detailed Description
Tracheostomy is often performed in patients after or anticipated prolonged mechanical ventilation, who are usually required oxygen therapy after discontinuation of mechanical ventilation.The high-flow tracheal (HFT) oxygen therapy in tracheostomized patients has been shown that can improve oxygenation,but can not induce positive end-expiratory pressure and elevation of end-expiratory lung volume. A modified HFT system by increasing expiratory resistance might induce PEEP and consequently elevate EELV.
Investigators
Jian-Xin Zhou
Professor
Capital Medical University
Eligibility Criteria
Inclusion Criteria
- •The tracheostomized patient requiring the convenient oxygen therapy.
Exclusion Criteria
- •Under 18 years;
- •history of esophageal, gastric or lung surgery;
- •The contraindication of using EIT (pacemaker, defibrillator, and implantable pumps).
Outcomes
Primary Outcomes
The mean end expiratory pressure.
Time Frame: the last 1 minutes of steady breathing during the standard or modified HFT.
The patients was delivering the high flow oxygen via the standard and modified HFT interface for 20 minutes.
Secondary Outcomes
- Changes in global and regional EELV(the last 1 minutes of steady breathing during the standard or modified HFT.)