Single-Incision Gasless Endoscopic Total Thyroidectomy Via Subclavian Approach Versus Open Surgery for PTC

Recruiting

• Conditions: Papillary Thyroid Carcinoma
• Interventions: Procedure: single-incision, gasless endoscopic total thyroidectomy with central compartment neck dissection; Procedure: conventional open surgery

• Registration Number: NCT06592755
• Lead Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Brief Summary

Historically, performing a contralateral thyroid lobectomy and lymph node dissection via the subclavian approach was considered challenging. This study aimed to evaluate the safety and feasibility of single-incision gasless endoscopic total thyroidectomy and central compartment neck dissection via the subclavian approach (SCA) in comparison to conventional open surgery for the treatment of papillary thyroid carcinoma (PTC) retrospectively.

Detailed Description

Historically, performing a contralateral thyroid lobectomy and lymph node dissection via the subclavian approach was considered challenging. This study aimed to evaluate the safety and feasibility of single-incision gasless endoscopic total thyroidectomy and central compartment neck dissection via the subclavian approach (SCA) in comparison to conventional open surgery for the treatment of papillary thyroid carcinoma (PTC) retrospectively.

Study Timeline

• Status Verified: 2024-09
• Study First Submitted: 2024-09-05
• Study First Submitted QC: 2024-09-10
• Study First Posted: 2024-09-19
• Study Start: 2024-09-20
• Last Update Submitted: 2024-09-29
• Primary Completion: 2024-09-30
• Study Completion: 2024-09-30
• Last Update Posted: 2024-10-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• (1) thyroid neoplasm <3.0 cm;
• (2) well differentiated papillary thyroid carcinoma.

Exclusion Criteria

• (1) extrathyroidal extensions estimated in ultrasonography scan;
• (2) enlarged lymph nodes in lateral neck compartment on palpation, or US scan;
• (3) suspected distant metastases;
• (4) previous history of neck radiation therapy and/or surgery.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
the Subclavian Approach group	single-incision, gasless endoscopic total thyroidectomy with central compartment neck dissection	The patients chose to undergo total thyroidectomy and central compartment neck dissection via the single-incision subclavian approach.
the conventional open surgery group	conventional open surgery	The patients chose to undergo total thyroidectomy and central compartment neck dissection via the conventional open surgery approach.

Primary Outcome Measures

Name	Time	Method
the disease-free survival	up to 24 months	The disease-free survival refers to the probability of survival without any biologic, structural, or functional events.

Trial Locations

Locations (1)

Sun Yat-sen Memorial Hospital; 🇨🇳 Guangzhou, Guangdong, China