NCT03298204已完成不适用
A Multicenter Analysis of Definitive (Chemo)Radiotherapy With or Without Chemotherapy for Patients With Esophageal Cancer - 3JECROG-R01
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 2,762
- 试验地点
- 1
- 主要终点
- Overall survival
研究概览
简要总结
The aim of this observational study is to retrospectively collect survival data for 3000 primary esophageal cancer patients from multicenter between January 2000 to present. Based on a Cox model, we want to develope a nomogram that predicts local recurrence, distant metastases, and survival for patients treated with radiotherapy or chemoradiotherapy with or without chemotherapy.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Histologically confirmed squamous cell carcinoma, adenocarcinoma of the esophageal or esophagogastric junction Unresectable or potentially resectable tumor (cT3-4N0-1M0-M1b, without visceral metastasis, according to AJCC 6th) based on standard primary staging by EUS and CT
- •Age>18 years
- •No distant metastasis other than supraclavicular lymph nodes
- •No prior history of thoracic radiation
- •Patients must have normal organ and marrow function as defined below: Leukocytes: greater than or equal to 3,500 G/L; Platelets: greater than or equal to 100,000/mm3 .Hemoglobin:greater than or equal to 10g/L .Total bilirubin: within normal institutional limits; AST/ALT: less than or equal to 1.5 times the upper limit; Creatinine within normal upper limits
排除标准
- •Patients with other cancer history except cervical carcinoma in situ and non-malignant melanoma skin cancer during 5 years before diagnosis of esophageal cancer
- •Pregnant or lactating females
- •Contraindication for radiotherapy or chemotherapy
结局指标
主要结局
Overall survival
时间窗: 2 year
次要结局
- Progress free survival(2 year)
- Locoregional recurrence free survival(2 year)
- Distant metastasis free survival(2 year)
研究者
Zefen Xiao
MD
Chinese Academy of Medical Sciences
研究点 (1)
Loading locations...
相似试验
招募中
不适用
Predicting Radiotherapy Response and Toxicities in Soft Tissue Sarcoma of the Extremities - Cohort BSoft Tissue Sarcoma of the ExtremitiesNCT05978024Royal Marsden NHS Foundation Trust150
已完成
不适用
chronOS Inject in Proximal Tibial FracturesClosed Proximal Tibial Fracture Schatzker I - VIClosed Proximal Tibial Fracture AO-OTA 41Closed Proximal Tibial Fracture AO-OTA 42NCT02056834Synthes GmbH36
已完成
不适用
N2 Lung Cancer Project: Neoadjuvant Treatment Followed Surgery Versus ChemoradiationNon-small-Cell Lung CarcinomaSurgeryStage IIIA-N2ChemoradiationSurvivalNCT02966769Grupo de Investigación Clínica en Oncología Radioterapia294
招募中
不适用
Multicenter Cohort Study of ESD and Chemo-radiotherapy for High-risk Early-stage Esophageal CancerEsophagus CancerNCT06385717Second Affiliated Hospital, School of Medicine, Zhejiang University120
已完成
不适用
Retrospective Observational Study Investigating Fluciclovine (18F) (FACBC)Prostatic NeoplasmsNCT02443571Blue Earth Diagnostics714