ACTRN12616001289404尚未招募未知
Determination of the metabolic health effects of breads made from wholemeal and refined high amylose wheat flour in healthy Australian adults
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
- CSIRO
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Prevention
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 65 Years（—）
- 性别
- All
入选标准
- •Males and females aged 18-65 years, BMI between 18.5 and less than or equal to 27.5 kg/m2, Normal fasting blood glucose concentration of 3.5 - 5.5 mmol/
排除标准
- •1. Known presence of diabetes
- •2. History of smoking in the past 6 months
- •3. Pregnant or lactating
- •4. Sufferers of bleeding disorders
- •5. Known food allergy, hypersensitivity or intolerance to wheat and/or starchy foods
- •6. Taking medications known to influence glucose tolerance or gastric emptying (oral contraceptives are excepted) such as the following lists which comprise the main classes of drugs prescribed for diabetes mellitus and those that alter gastric emptying respectively:
- •Diabetes mellitus: Biguanides;Sulphonylureas; Meglitinide derivatives; Alpha-glucosidase inhibitors; Thiazolidinediones (TZDs); Glucagonlike peptide-1 (GLP-1) agonists; Dipeptidyl peptidase IV (DPP-4) inhibitors; Selective sodium- glucose transporter-2 (SGLT-2) inhibitors; Insulins; Amylinomimetics; Bile acid sequestrants; Dopamine agonists
- •Gastric emptying: Atropine and anticholinergics; Certain antihistamines (diphenhydramine, promethazine); Tricyclic antidepressants; Phenothiazines; Sympathomimetics; Nitrites; anticholinesterases; Sedative hypnotics; Antacids
- •7. Persons considered by the investigator to be unwilling, unlikely or unable to comprehend or comply with the study protocol
- •8. Participation in another research study within 30 days preceding the start of this study
- •9. Known history or presence of gastrointestinal, renal or hepatic disease of any cause
- •10. Night shift workers
研究者
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