Alleviation of Neuropathic Scar Pain With Autologous Fat Graft
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Visual Analogue Scale (VAS)
研究概览
简要总结
Traumatic wounds inflict small- and large-fiber sensory nerve damage, causing neuropathic pain in scar tissue. Autologous fat grafting has been clinically shown to improve scar quality, but scantly study has explored its effects on pain. The aim of the study was to survey its effect on pain.
详细描述
Methods: From February 2008 and June 2013, a total of 36 patients received autologous fat grafting in scar areas. Patients who Douleur Neuropathique 4 Questions (scores >4/10) were enrolled this study. The Visual Analogue Scale (VAS), and Neuropathic Pain Symptom Inventory (NPSI) were used to evaluate pain preoperatively and postoperatively after 1 week, 4 weeks, and 24 weeks. The mechanism of trauma, duration of allodynia, fat graft volume, and total follow-up time were recorded.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 19 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •February 2008 and June 2013, patients received autologous fat grafting in scar areas and also had pain over scar area before surgery
排除标准
- •patients refused to participate the study
结局指标
主要结局
Visual Analogue Scale (VAS)
时间窗: preoperatively and postoperatively after 1 week, 4 weeks, and 24 weeks.
次要结局
- Neuropathic Pain Symptom Inventory (NPSI)(preoperatively and postoperatively after 1 week, 4 weeks, and 24 weeks)