Comparative Evaluation of the Full Outline of UnResponsiveness (FOUR) Score and Glasgow Coma Scale in Predicting Clinical Outcomes in Patients With Altered Mental Status Presenting to the Emergency Department: A Prospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 240
- 试验地点
- 1
- 主要终点
- In hospital mortality
研究概览
简要总结
The goal of this observational study is to compare the predictive utility of the Full Outline of Unresponsiveness (FOUR) Score and the Glasgow Coma Scale (GCS) Score in determining outcomes among patients with altered mental status admitted to the emergency room. The main questions it aims to answer are:
Does the FOUR Score provide a more accurate prediction of patient outcomes than the GCS Score? Are there specific patient subgroups where one score is more effective than the other?
Participants will:
Undergo assessment of mental status using both the FOUR Score and the GCS Score during their emergency room admission.
Have their clinical outcomes monitored during their hospital stay.
详细描述
The Glasgow Coma Scale (GCS) is commonly used for neurological assessment, but it lacks the precision to cover the full range of consciousness changes.[1]
The GCS is a 15-point scale used to assess consciousness based on three components:
Eye Opening (E):
Spontaneous (4 points) To verbal command (3 points) To pain (2 points) No response (1 point)
Verbal Response (V):
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients admitted to the emergency room with altered mental status.
- •Patients were assessed using both the Full Outline of Unresponsiveness (FOUR) Score and the Glasgow Coma Scale (GCS) Score upon admission.
- •Patients whose clinical outcomes (e.g., mortality, length of hospital stay, need for intensive care) are available for follow-up and analysis.
排除标准
- •Patients with incomplete or missing data on FOUR and/or GCS assessments.
- •Patients who leave against medical advice (LAMA) or are discharged before outcome data can be collected.
- •Patients with pre-existing neurological conditions that might independently influence outcomes (e.g., severe dementia, long-standing neurodegenerative diseases).
- •Patients in whom resuscitative measures were initiated but unsuccessful before scoring could be performed.
结局指标
主要结局
In hospital mortality
时间窗: average of 10 days through discharge
Mortality (death) during hospitalization
Accuracy Assessment of the Glasgow Coma Scale (GCS)
时间窗: the first 12 hours after ER admission
Glasgow Coma Scale (GCS): Range 3-15; higher scores indicate better neurological status.
Accuracy Assessment of the Full Outline of UnResponsiveness (FOUR) Score
时间窗: the first 12 hours after ER admission
Full Outline of Unresponsiveness (FOUR) score: Range 0-16; higher scores indicate better neurological status.
次要结局
- Length of Hospitalization(average of 10 days through discharge)
研究者
Abdul-Ilah R. Khamis
Principal Investigator
Al-Nahrain University