Study to compare different drugs with different routes in nasal surgery to compare blood loss, visiblity and better outcome.
Not Applicable
- Conditions
- Health Condition 1: J019- Acute sinusitis, unspecified
- Registration Number
- CTRI/2020/05/025037
- Lead Sponsor
- I
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA physical status grade I and II
Exclusion Criteria
1. patients on any of the study drugs prior to surgery
2. patients with known hypersensitivity to study drugs
3. patients having history of drug abuse
4. patients who are mentally retarded
5. coagulation defects
6. conditions contraindicated for induced hypotension
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method to evaluate the efficacy of intravenous dexmedetomidine, oral metoprolol as a premedicant with inhalational sevoflurane for inducing hypotension in terms of mean arterial blood pressure and surgical field visibilityTimepoint: baseline, every minute for first 5 minutes, every 5 minutes for next 15 minutes and then every 15 minutes till the end of surgery <br/ ><br>
- Secondary Outcome Measures
Name Time Method to study the incidence of intra-operative and post-operative complications associated with study drugs or technique of induced hypotensionTimepoint: intraoperatively and upto 24 hours after surgery <br/ ><br>