Photorefractive Keratectomy and Corneal Cross-linking in Keratoconus

Not Applicable

Completed

• Conditions: Keratoconus
• Interventions: Procedure: Simultaneous Photorefractive Keratectomy and Collagen Cross-linking in patients with keratoconus

• Registration Number: NCT02189447
• Lead Sponsor: The Eye Center and The Eye Foundation for Research in Ophthalmology

Brief Summary

Evaluation of the safety and efficacy of surface ablation followed by Collagen Cross-linking in patients with keratoconus

Detailed Description

Not available

Study Timeline

• Study Start: 2011-01
• Primary Completion: 2013-09
• Study Completion: 2013-09
• Status Verified: 2014-07
• Study First Submitted: 2014-07-05
• Study First Submitted QC: 2014-07-10
• Last Update Submitted: 2014-07-10
• Study First Posted: 2014-07-14
• Last Update Posted: 2014-07-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

• contact lens intolerance
• corneal thickness > 450 micrometers
• Keratometry < 56 diopters
• Astigmatism < 6 diopters

Exclusion Criteria

• corneal thickness < 450 micrometers
• Keratometry > 56 diopters
• Astigmatism > 6 diopters

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Refractive surgery	Simultaneous Photorefractive Keratectomy and Collagen Cross-linking in patients with keratoconus	Patients with keratoconus treated with simultaneous photorefractive keratectomy and Corneal collagen cross-linking.

Primary Outcome Measures

Name	Time	Method
The change of visual acuity following Photorefractive Keratectomy and Corneal Collagen Cross-linking in patients with Keratoconus	6 months	The change of visual acuity from baseline in patients suffering from keratoconus following treatment with Photorefractive Keratectomy and Corneal Collagen Cross-linking.