CTIS2024-512901-22-00进行中(未招募)1 期
tility of intra-abdominal pressure and clinical ultrasound for guiding diuretic treatment in patients with acute heart failure - PI23/00797
Fundacion Instituto De Investigacion Sanitaria Aragon0 个研究点目标入组 168 人开始时间: 2024年5月21日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中(未招募)
- 发起方
- 入组人数
- 168
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 65+(—)
- 性别
- All
入选标准
- •Men or women over 18 years of age, Diagnosis of HF based on the latest HF guidelines published in 2022, NT-proBNP > 1000 pg/mL or BNP > 250 pg/mL, Bladder catheterization in order to perform intra-abdominal pressure measurement, Intravascular or mixed pattern of congestion, defined as the presence of one or more clinical signs of congestion (edema, ascites and/or pleural effusion), Signature of the informed consent
排除标准
- •Patient with stay in the internal medicine department > 24 hours, Systolic blood pressure at admission < 100 mmHg, Heart rate at admission > 170 beats per minute (bpm), Cardiogenic shock, Acute myocardial ischemia, Patients receiving renal replacement therapy (ultrafiltration or peritoneal dialysis)., Patients whose origin is the Intensive Care Unit, Renal transplant recipients, Serum hemoglobin < 9 g/dL, Pregnancy or lactation, Previous history of hypersensitivity to hydrochlorothiazide or furosemide., Patients with recent cardiac surgery (last year) or cardiac transplant recipients, Need for inotropic support to maintain adequate cardiac and/or renal output, Absence of sufficient clinical congestion (ADVOR score = 0 at the time of randomization), Patient refusal to participate in the clinical trial, Inability or contraindication to bladder catheterization
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