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Assistive ExoSkeletons to Enable Wearable Rehabilitation Robotics

Not Applicable
Completed
Conditions
Diabetic Foot Ulcer
Diabetic Foot Ulcer Associated With Type II Diabetes Mellitus
Interventions
Device: Exoskeleton
Registration Number
NCT03717233
Lead Sponsor
Results Group LLC
Brief Summary

Study will evaluate the use of lower-limb assistive exo-skeletons worn on the ankle and foot. Participants will wear the exo-skeletons and walk in a safe environment. Measurements will be taken to determine how the exo-skeletons affect the pressure on the feet of people with diabetic foot ulcer and how they walk.

Detailed Description

Study will evaluate the use of lower-limb assistive exo-skeletons worn on the ankle and foot. Participants will include those with self-described history of Diabetic Foot Ulcer and age-matched healthy volunteers. Participants will wear the exo-skeletons and will be asked to walk 32 feet, and to stand quietly for 30 seconds.

Measurements will be taken to evaluate how the exoskeletons affect how people walk, and will also evaluate the pressure on the bottom of their feet. These measurements will be repeated multiple times to evaluate four different exo-tendon spring rates, and two sets of control shoes.

Exo-skeletons have been shown to reduce the pressure on the bottoms of people's feet and to reduce the effort to walk. This study is necessary to understand the contribution of different levels of exo-skeleton spring force to these effects.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
40
Inclusion Criteria
  • Self-reported history of diabetic foot ulcer
Exclusion Criteria
  • Unable to continuously ambulate/walk ≥ 40 feet without an assistive device, such as a cane or walker
  • Signs/symptoms of an infected foot lesion/ulcer as determined by a basic foot exam
  • Trans-metatarsal foot amputation or more significant amputation.
  • Symptomatic for signs/symptoms of cardiovascular disease as determined from interpretation of the 2017 PAR-Q+ (predicated on participant responses of "yes" indicating symptomatic/unstable medical conditions to page 2 and page 3 of the 2017 PAR-Q)
  • Participants will be excluded from this study if they demonstrate pre-participation, or chronic, signs/symptoms of hypoglycemia: Confusion, unusual headache, unusual visual disturbances, self-reported mental dullness, shakiness, self-reported weakness, abnormal sweating, undue nervousness/anxiety, and/or tingling of the mouth, toes, and/or fingers or if they answer yes to question 5b and 5c of the 2017 PAR-Q+ .
  • Participants will be temporarily excluded from this study if they are symptomatic for acute illness such as cold or fever. If the participant is symptomatic for acute illness such as cold or fever, participation will be reconsidered upon illness resolution.
  • If participants answer yes to question 4a of the 2017 PAR-Q+ and if they demonstrate pre-study participation resting blood pressure < 90/60 mmHg and >140/90 mmHg .

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Primary ArmExoskeletonParticipants will be used as their own controls. Participants will be evaluated using exo-skeletons with non-motorized spring elements in parallel to the Achilles tendon. Up to 5 different levels of spring force will be evaluated to evaluate the impact upon plantar pressure and measures of fall risk.
Primary Outcome Measures
NameTimeMethod
Forefoot plantar pressure30 minutes

Measurements of the force and pressure on the bottom of the front of the foot

Secondary Outcome Measures
NameTimeMethod
Measures of fall risk30 minutes

Measurements of postural sway, balance and gait speed to provide an indication of participant's risk of falling while wearing different shoes.

Trial Locations

Locations (2)

Rancho Los Amigos

🇺🇸

Los Angeles, California, United States

Southern CT State University

🇺🇸

New Haven, Connecticut, United States

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