Assesment of the Effectiveness of Amniotic Membrane Seeded by Whartons' Jelly Stem Cells plus Coronally Advanced Flap for the Treatment of Gingival Recessio

Not Applicable

• Conditions: Gingival Recession.; Gingival recession; K06.0

• Registration Number: IRCT20210330050791N1
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 30 August 2021

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Patients aged 18 or more
Patients who have read, understood, and signed an informed consent form
Patients who have been able and willing to follow study procedures and instructions
Patients who have at least one tooth with buccal Miller class I or II recession type defects
Recessions with = ? mm depth and = ?mm width in premolar, canine or incisor area, with probing depths =? mm and = ? mm keratinized tissue
Treating only one tooth at each side as a test or control tooth in case of adjacent teeth with recession defects

Exclusion Criteria

?ubjects who are participating in other clinical trials
Subjects who have a history of cancer or human immunodeficiency virus
Subjects who have an uncontrolled systemic disease with compromised healing potential (such as diabetes mellitus with a recent HbA?c > ?%)
Using medications known to cause gingival enlargement and anticoagulants with International Normalized Ratio (INR) > ?.? and taking herapeutic doses of medications known to affect bone metabolism
Those who fail to maintain good plaque control
Teeth with extremely prominent root surfaces
Teeth with Class V restorations extending to root surfaces
Subjects who have any systemic acute infections in the areas intended for surgery
Female subjects who are pregnant or lactating
History of surgical periodontal treatment of the involved site
Severe tooth malposition or open contacts
Current or planned orthodontic treatment during the ?-month course of the study
Molars; teeth with axial mobility; teeth with interproximal loss of attachment; teeth with crowns or veneers causing an undetectable CEJ
Patients with a frenum and/or muscle attachment encroaching on marginal gingiva in the first ? weeks after frenectomy procedure
History of weekly or more frequent use of smokeless chewing tobacco, pipe or cigar smoking and cigarette smoking within the previous ? months

Study & Design

• Study Type: interventional
• Study Design: Not specified