IRCT20210330050791N1
Completed
未知
Clinical comparison of coronally advanced flap plus amniotic membrane seeded with whartons' jelly mesenchymal stem cells and subepithelial connective tissue graft in the treatment of single Miller's class I and II gingival recessions
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Shiraz University of Medical Sciences
- Enrollment
- 20
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients aged 18 or more
- •Patients who have read, understood, and signed an informed consent form
- •Patients who have been able and willing to follow study procedures and instructions
- •Patients who have at least one tooth with buccal Miller class I or II recession type defects
- •Recessions with \= ? mm depth and \= ?mm width in premolar, canine or incisor area, with probing depths \=? mm and \= ? mm keratinized tissue
- •Treating only one tooth at each side as a test or control tooth in case of adjacent teeth with recession defects
Exclusion Criteria
- •?ubjects who are participating in other clinical trials
- •Subjects who have a history of cancer or human immunodeficiency virus
- •Subjects who have an uncontrolled systemic disease with compromised healing potential (such as diabetes mellitus with a recent HbA?c \> ?%)
- •Using medications known to cause gingival enlargement and anticoagulants with International Normalized Ratio (INR) \> ?.? and taking herapeutic doses of medications known to affect bone metabolism
- •Those who fail to maintain good plaque control
- •Teeth with extremely prominent root surfaces
- •Teeth with Class V restorations extending to root surfaces
- •Subjects who have any systemic acute infections in the areas intended for surgery
- •Female subjects who are pregnant or lactating
- •History of surgical periodontal treatment of the involved site
Outcomes
Primary Outcomes
Not specified
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