Myocardialbridge Bypass Graft Surgery Efficacy Verification
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- All-Cause Mortality
研究概览
简要总结
Myocardial Bridge Bypass Graft surgery is introduced to relieve the unmedical symptoms of patients with long-segment or deep myocardial bridge, clinical outcomes will be collected to verify the effectiveness of the surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with myocardialbridge requiring drug therapy or surgical intervention.
排除标准
- •patients with myocardialbridge not requiring drug therapy or surgical intervention, or unwilling to be enrolled for any reason
研究组 & 干预措施
MyocardialBridge Bypass Graft
The patients with deep(depth>2mm) and long-segement(length>25mm) of myocardialbridge receiving myocardialbridge bypass graft surgery(MBBG)，fulfilling the following criteria: 1.presenting with pectoris angina that cannot be effectively relieved by maximum guideline-directed drug therapy; 2. No atherosclerotic plaque or merely mild atherosclerotic stenosis is detected at the proximal or entry of the myocardialbridge confirmed by coronory artery angiography.
干预措施: MBBG (Procedure)
Myocardialbridge CABG
The patients with deep(depth>2mm) and long-segement(length>25mm) of myocardialbridge will be allocated to receive myocardialbridge bypass graft surgery(MBBG)，when fulfilling the following criteria: 1.presenting with pectoris angina that cannot be effectively relieved by maximum guideline-directed drug therapy; 2. The moderate-to-severe atherosclertotic stenosis is detected at the proximal or entry of the myocardialbridge confirmed by coronory artery angiography.
干预措施: MB CABG (Procedure)
Myocardioalbridge Unroof
The patients with superficial type(depth<2mm) and short-segement(length<25mm) of myocardial bridge will be allocated to receive "unroof" surgery，when fulfilling the following criteria: 1.presenting with pectoris angina that cannot be effectively relieved by maximum guideline-directed drug therapy; 2. No atherosclerotic plaque or merely mild atherosclerotic stenosis is detected at the proximal or entry end of the myocardialbridge confirmed by coronory artery angiography.
干预措施: MB unroof (Procedure)
结局指标
主要结局
All-Cause Mortality
时间窗: Up to 240 months
Rate of counduit patency
时间窗: Up to 180 months
次要结局
未报告次要终点
研究者
Wang zhen
Principal Investigator
Xi'an International Medical Center Hospital