Pharmacokinetics of Carnosine

Not Applicable

Completed

• Conditions: Oxidative Stress
• Interventions: Dietary Supplement: pure carnosine; Other: Beef; Other: Chicken; Other: Chicken broth

• Registration Number: NCT00721708
• Lead Sponsor: Tufts University

Brief Summary

The absorption kinetics of dietary carnosine (β-alanyl-L-histidine) will be determined in the healthy adults.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-04
• Primary Completion: 2007-10
• Study Completion: 2008-07
• Study First Submitted: 2008-07-22
• Study First Submitted QC: 2008-07-23
• Study First Posted: 2008-07-24
• Status Verified: 2009-12
• Last Update Submitted: 2009-12-14
• Last Update Posted: 2009-12-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 4

Inclusion Criteria

• Healthy adult
• normal hematological parameters, normal serum albumin, normal liver function, normal kidney function

Read More

Exclusion Criteria

• History of smoking or alcoholism

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
1	pure carnosine	Carnosine(450 mg)
2	Beef	Beef (150g)
3	Chicken	chicken (150g)
4	Chicken broth	Chicken broth (obtained from 150 g of chicken breast)

Primary Outcome Measures

Name	Time	Method
Plasma histidine-dipeptide	0, 30, 60, 100, 180, 240, & 300 min

Trial Locations

Locations (1)

Jean Mayer USDA-Human Nutrition Research Center on Aging at Tufts University; 🇺🇸 Boston, Massachusetts, United States