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Clinical Trials/NCT04997174
NCT04997174
Unknown
Not Applicable

Comparison of Postoperative Pain Management in Patients Undergoing Laparoscopic Colorectal Surgery Under Enhanced Recovery After Surgery (ERAS) Program, Laparoscopic Colorectal Surgery Without ERAS and Open Colorectal Surgery

Prince of Songkla University1 site in 1 country162 target enrollmentOctober 2021
InterventionsCelecoxib

Overview

Phase
Not Applicable
Intervention
Celecoxib
Conditions
Postoperative Pain
Sponsor
Prince of Songkla University
Enrollment
162
Locations
1
Primary Endpoint
Pain intensity
Last Updated
4 years ago

Overview

Brief Summary

This is a retrospective study to compare postoperative pain intensity in patients going laparoscopic colorectal surgery with Enhanced Recovery after Surgery (ERAS), without ERAS and open colorectal surgery.

Detailed Description

This study is a matched case-control study. Control patients will be matched to ERAS cases in a 1:1:1 ratio (laparoscopic surgery with ERAS protocol : laparoscopic surgery without ERAS protocol : open surgery).

Registry
clinicaltrials.gov
Start Date
October 2021
End Date
December 2022
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Sasikaan Nimmaanrat

Associate Professor

Prince of Songkla University

Eligibility Criteria

Inclusion Criteria

  • Patients undergoing colorectal surgery under ERAS program and those with the same sort of laparoscopic surgery without ERAS program as well as those with open colorectal surgery with complete required recorded data.

Exclusion Criteria

  • Patients with incomplete required data on record.
  • Those with any major intraoperative or postoperative complications.

Arms & Interventions

ERAS

Patients undergoing laparoscopic colorectal surgery with ERAS

Intervention: Celecoxib

Outcomes

Primary Outcomes

Pain intensity

Time Frame: Until discharge (5-7 days)

Pain score (Verbal Numerical Rating Scale: VNRS) after surgery, VNRS consists of 0-10, where 0 means no pain and 10 means worst pain imaginable

Secondary Outcomes

  • Opioid(Until discharge (5-7 days))

Study Sites (1)

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