Descurainia Sophia in hemodialysis patients

Phase 2

• Conditions: N18.5; hemodialysis patients.; Chronic kidney disease, stage 5

• Registration Number: IRCT20170725035305N3
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 October 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

age between 18 - 70 years old
on hemodialysis for more than 3 months
KT/V > 1.2
insensitive to D. Sophia or any herbal remedy
no history of active infection in the past month
using AVF for Hemodialysis

Exclusion Criteria

sensitivity to D. Sophia or any herbal remedy
history of active infection in the past month
unwilling to participate for any reason
using permcath or AVG for hemodialysis
hospital admission for any reason in past month and during the study period.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
MDA (Malondialdehyde). Timepoint: At the start of the study, before wash out, after wash out and at the end of the study. Method of measurement: serum level and biochemistry analysis.;Potassium serum level. Timepoint: At the start of the study, before wash out, after wash out and at the end of the study. Method of measurement: blood sample.;Lipid profile. Timepoint: At the start of the study, before wash out, after wash out and at the end of the study. Method of measurement: blood sample.;Total antioxidation capacity. Timepoint: At the start of the study, before wash out, after wash out and at the end of the study. Method of measurement: blood sample.;Hemocystein serum level. Timepoint: At the start of the study, before wash out, after wash out and at the end of the study. Method of measurement: blood sampling.

Secondary Outcome Measures

Name	Time	Method
Thirst intensity. Timepoint: At the start of the study, before wash out, after wash out and at the end of the study. Method of measurement: using Visual Analogue Scale.