The Association Between Intraoperative Hypotension and Perioperative Stroke in General Surgery Patients: a Retrospective, Hospital-based Study in China
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Perioperative Complication
- Sponsor
- Qianfoshan Hospital
- Enrollment
- 70000
- Locations
- 1
- Primary Endpoint
- Incidence of perioperative stroke
- Last Updated
- 5 years ago
Overview
Brief Summary
The aim of this study is to investigate the association between the severity and duration of intraoperative hypotension and the incidence of perioperative stroke after non-cardiac and non-neurologic surgeries.The secondary aim of this study is to confirm the potential risk factors of the perioperative stroke.
Detailed Description
Optimized intraoperative management may play an important role in perioperative stroke prevention. Maintaining blood pressure near preoperative baseline values may help decrease the incidence of stroke, however the related evidence is limited.Therefore, this study is to investigate the association between intraoperative hemodynamic variable and the risk of perioperative stroke after non-cardiac and non-neurologic surgeries. The secondary aim of this study is to establish the potential risk factors of the perioperative stroke.
Investigators
Lili Cao
Professor
Qianfoshan Hospital
Eligibility Criteria
Inclusion Criteria
- •Patients underwent surgeries in First hospital affiliated to Shandong First Medical University from January 2013 to October 2019
- •Age\>18 or older
Exclusion Criteria
- •Patients received local infiltration anesthesia
- •Patients underwent total intravenous anesthsia without tracheal intubation or Laryngeal Mask Airway insertion
- •Major vascular operation
- •Neurologic surgery
- •Cariac surgery
- •Intraoperative blood pressure measurements or postoperative neuroimagings measurements are not available
- •History of severe neurological or psychiatric disease
Outcomes
Primary Outcomes
Incidence of perioperative stroke
Time Frame: Within 30 days after surgery
Perioperative stroke diagnosed with CT or MRI examination, symptoms and signs
Secondary Outcomes
- Rate of death(Within 30 days after surgery)
- Expense of Healthe care and social service(Through study completion, an average of 14 days)