The Association Between Intraoperative Hypotension and Perioperative Stroke in General Surgery Patients: a Retrospective, Hospital-based Study in China
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 70,000
- 试验地点
- 1
- 主要终点
- Incidence of perioperative stroke
研究概览
简要总结
The aim of this study is to investigate the association between the severity and duration of intraoperative hypotension and the incidence of perioperative stroke after non-cardiac and non-neurologic surgeries.The secondary aim of this study is to confirm the potential risk factors of the perioperative stroke.
详细描述
Optimized intraoperative management may play an important role in perioperative stroke prevention. Maintaining blood pressure near preoperative baseline values may help decrease the incidence of stroke, however the related evidence is limited.Therefore, this study is to investigate the association between intraoperative hemodynamic variable and the risk of perioperative stroke after non-cardiac and non-neurologic surgeries. The secondary aim of this study is to establish the potential risk factors of the perioperative stroke.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients underwent surgeries in First hospital affiliated to Shandong First Medical University from January 2013 to October 2019
- •Age>18 or older
排除标准
- •Patients received local infiltration anesthesia
- •Patients underwent total intravenous anesthsia without tracheal intubation or Laryngeal Mask Airway insertion
- •Major vascular operation
- •Neurologic surgery
- •Cariac surgery
- •Intraoperative blood pressure measurements or postoperative neuroimagings measurements are not available
- •History of severe neurological or psychiatric disease
结局指标
主要结局
Incidence of perioperative stroke
时间窗: Within 30 days after surgery
Perioperative stroke diagnosed with CT or MRI examination, symptoms and signs
次要结局
- Rate of death(Within 30 days after surgery)
- Expense of Healthe care and social service(Through study completion, an average of 14 days)
研究者
Lili Cao
Professor
Qianfoshan Hospital