NL-OMON33175
Recruiting
Phase 2
Safety and feasibility of the ketogenic diet in therapy resistand paediatric recurrent or progressive pontine glioma, a pilot study - Pontine glioma and ketogenic diet
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Erasmus MC, Universitair Medisch Centrum Rotterdam
- Enrollment
- 10
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- recurrent or progressive pons glioma
- •\- 1\-18 years of age
- •\- failure of treatment with radiotherapy and Temozolomide and no therapeutic options left
- •\- good Dutch reading and writing (parents of caregivers)
- •\- Informed Consent of parents/care givers and/or the child (when \>12\)
- •\- willingness of children younger than 12 years to participate in the study
Exclusion Criteria
- •\- \< 1 year or \>17 year of age
- •\- use of Temozolomide or other chemotherapeutic drug
- •\- language barrier (parents or caregivers)
- •\- current treatment with steroids of treated within 3 weeks before start of the study
- •\- fatty acid disorders (like MCAD)
- •\- Hypertrigyceridemia (\> 10mmol/l)
- •\- kidney stones
- •\- diabetes mellitus
- •\- pancreatitis
- •\- gastro intestinal problems like persistent diarrhoea
Outcomes
Primary Outcomes
Not specified
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