DRKS00032390
Recruiting
Not Applicable
Abscopal effects in metastasized cancer patients treated with radiotherapy and immune checkpoint inhibition - ARTIC
niversitätsklinikum Köln0 sites62 target enrollmentJuly 31, 2023
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Abscopal effects under radio-immunotherapy of all tumour entities treated with it
- Sponsor
- niversitätsklinikum Köln
- Enrollment
- 62
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients with documented evidence of metastatic solid tumor of any entity and simultaneous RT\-ICI between 06/2015 (start ICI) and 06/2021 (end RT) at participating centers.
- •\- At least one lesion outside the irradiation field: non\-irradiated lesion (outside the 10% isodose, NIL)
- •\- Radiological images of the NILs prior to initiation of RT (at least two) and after the end of RT (at least one) to exclude an effect induced by ICI only
Exclusion Criteria
- •\- Start of another systemic therapy during the time period being analyzed
- •\- Inadequate imaging to assess abscopal effect or exclude response induced by ICI only
Outcomes
Primary Outcomes
Not specified
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