The (cost-)effectiveness of a combined lifestyle intervention in overweight and obese patients with knee osteoarthritis in primary care

Recruiting

• Conditions: Knee osteoarthritis; layman: Knee arthritis; 10023213

• Registration Number: NL-OMON54019
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 234

Inclusion Criteria

o First presentation at GP of knee complaints within previous 24 months
o Aged between 45 and 70 years
o NICE guideline diagnosis of clinical knee OA
(i.e. aged 45 or over and activity related joint pain and either
no morning joint-related stiffness or
morning stiffness that lasts no longer than 30 minutes)
o Presence of overweight or obesity (BMI >=25 kg/m2)

Exclusion Criteria

o Other pathological conditions that could explain the joint complaints like
traumatic onset knee complaints or
presence of other forms of arthritis (rheumatoid arthritis,
psoriatic arthritis) or
pre-patellar bursitis or patellar tendinitis
o Any lower extremity condition other than knee OA resulting in physical
impairment that will limit GLI participation.
o Contraindications for MRI
o Previously participated in a GLI.
o Inability to understand the Dutch language

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>5kg or 5% weight reduction after 24 months</p><br>