corneal crosslinking in keratoconus patients

Phase 2

• Conditions: Keratoconus.; Keratoconus; H18.6

• Registration Number: IRCT20190508043529N1
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 October 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 124

Inclusion Criteria

Progressive keratoconus (Progression of the disease was considered as confirmed if the loss of corrected distance visual acuity (CDVA) was more than one line in 1 year, or when the topographic keratometry increased by >1.0 D in 6 months or >2.0 D in 12 months)
The thinnest central corneal thickness (CCT) >400 µm

Exclusion Criteria

Patients who wear contact lenses for one month prior to the initial evaluation and treatment
Patients with immune system disorders
Patients with corneal scar
Patients with history of herpes simplex keratitis
Patients who were pregnant or breastfeeding

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Best corrected spectacle visual acuity (BSCVA). Timepoint: 6 months after intervention. Method of measurement: E-chart.

Secondary Outcome Measures

Name	Time	Method
Keratometric indices. Timepoint: 6 months after intervention. Method of measurement: Pentacam.;Biomechanical parameters. Timepoint: 6 months after intervention. Method of measurement: Corvis.