Comparison of Intubating Conditions in 25° Head-up Position and Strict Supine
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,000
- 试验地点
- 8
- 主要终点
- POGO score
研究概览
简要总结
Tracheal intubation, particularly before surgery, is traditionally done in supine position. It was shown in the general population and in obese patients in particular, that the pre-oxygenation in a 25° head-up position provided a better efficiency of the pre-oxygenation and an apnea time longer. This position would also allow for better intubation conditions in direct laryngoscopy.
The investigators intend to assess two different patient's intubation position : supine position and 25° head-up position
详细描述
Randomization assigned in random block, stratification by operator (20 patients per operator, 10 in each group).
Interim analysis every 100 patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
盲法说明
No masking
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •- patients scheduled for various surgeries requiring general anesthesia with curare, with intubation of the trachea, eligible for intubation by direct laryngoscopy.
- •> 18 years
- •patients with social security
排除标准
- •Emergency surgery.
- •Patient who requiring rapid sequence induction.
- •Intubation without curare.
- •Expected difficult intubation with planned modification of the intubation protocol (i. e. intubation under fibroscopy, airtrach or videolaryngoscopy)
- •Patient with a history of epilepsy, pulmonary or cardiovascular disease (including ischemic heart disease, symptomatic asthma or obstructive pulmonary disease).
- •Patient with mask phobia.
- •BMI> 30kg / m2
- •Patient who are refusing to take part.
- •Patient protected major, minor, pregnant women, patients deemed incapable of giving informed consent.
结局指标
主要结局
POGO score
时间窗: at day 1
valid score observed by the anesthetist performing intubation at the time of intubation. POGO score means Percentage of Glottic Opening : from 0% (none visualization of the glottic opening, worst result) to 100% (complete visualization of the glottic opening, best result), from the anterior curvature of the vocal cords to the interarytenoid node, between the posterior cartilage
次要结局
- Episodes of desaturation and episodes of hypotension(at ady 1)
- Mechanical complications of intubation:(at day 1)
- Patient height(at day 1)
- Cormack-Lehane grade(at day 1)
- Intubation operator's comfort(at day 1)