Prospective and retrospective analysis of amyloidosis patients : Early diagnosis and prognosis factor of amyloidosis
- Conditions
- Diseases of the blood and blood -forming organs and certain disorders involving the immune mechanism
- Registration Number
- KCT0000864
- Lead Sponsor
- Korea Centers for Disease Control and Prevention
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion criteria
1) Patients were histologically verified amyloidosis deposition at least one or more organ
Or Patients were reasonable to be diagnosed a cardiac amyloidosis on echocardiography or heart magnetic resonance imaging increasing with immunoglobulin light chain in serum or urine.
- Echocardiography results: mean left ventricular wall thickness >12mm and patients who have no other cardiovascular disease such as valve disease or hypertension
- Heart magnetic resonance imaging results:
Gadolinium delayed enhancement in a wide range of endocardium
2) Patients who were aged 20 years or older
3) Patients who were obtained consent form to participate the research
4) Patients who were written consent form to genetic and biochemical test for research purpose using bone marrow, peripheral blood and tissue obtained for diagnostic purpose
Exclusion criteria
Patients who do not agree with this study and biochemical and genetic examination
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method motality at anytime
- Secondary Outcome Measures
Name Time Method treatment response