Physical Activity in Patients After Aortic Valve Replacement (Valve-ex)

Not Applicable

• Conditions: Valvular Aortic Stenosis
• Interventions: Other: Physical activity; Other: no Intervention

• Registration Number: NCT00860678
• Lead Sponsor: Technical University of Munich

Brief Summary

A structured and supervised, 3-month physical activity intervention in patients after aortic valve replacement due to severe stenosis, accompanied by examination of cardiac size and function, exercise capacity and endothelial function before, three and six months after operation; comparison with a non-intervention control group.

Detailed Description

Not available

Study Timeline

• Status Verified: 2009-03
• Study First Submitted: 2009-03-11
• Study First Submitted QC: 2009-03-11
• Last Update Submitted: 2009-03-11
• Study First Posted: 2009-03-12
• Last Update Posted: 2009-03-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Patients with severe valvular aortic stenosis and indication for valve replacement

Exclusion Criteria

• Coronary heart disease with indication for additional bypass surgery Leading insufficiency of the valve
• Age < 65 or > 75
• Diseases or conditions leading to additional risks during physical activity (e.g. diabetes, arthrosis, obstructive pulmonary disease)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
A	Physical activity	Training group
B	no Intervention	Controls

Primary Outcome Measures

Name	Time	Method
Maximum oxygen uptake

Trial Locations

Locations (1)

Department of Prevention and Sports Medicine Technische Universität München; 🇩🇪 München, Bavaria, Germany