Physical Activity in Patients After Aortic Valve Replacement (Valve-ex)
Not Applicable
- Conditions
- Valvular Aortic Stenosis
- Registration Number
- NCT00860678
- Lead Sponsor
- Technical University of Munich
- Brief Summary
A structured and supervised, 3-month physical activity intervention in patients after aortic valve replacement due to severe stenosis, accompanied by examination of cardiac size and function, exercise capacity and endothelial function before, three and six months after operation; comparison with a non-intervention control group.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
- Patients with severe valvular aortic stenosis and indication for valve replacement
Exclusion Criteria
- Coronary heart disease with indication for additional bypass surgery Leading insufficiency of the valve
- Age < 65 or > 75
- Diseases or conditions leading to additional risks during physical activity (e.g. diabetes, arthrosis, obstructive pulmonary disease)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Maximum oxygen uptake
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link physical activity to improved endothelial function post-aortic valve replacement?
How does structured physical activity compare to standard postoperative care in enhancing exercise capacity after aortic valve replacement?
Which biomarkers are associated with cardiac remodeling and endothelial function in patients with valvular aortic stenosis undergoing physical activity interventions?
What are the potential adverse events of a 3-month supervised physical activity program in post-aortic valve replacement patients and how are they managed?
Are there combination approaches involving physical activity and pharmacological agents to optimize cardiac outcomes in aortic stenosis patients post-surgery?
Trial Locations
- Locations (1)
Department of Prevention and Sports Medicine Technische Universität München
🇩🇪München, Bavaria, Germany
Department of Prevention and Sports Medicine Technische Universität München🇩🇪München, Bavaria, Germany