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临床试验/NCT01589900
NCT01589900已完成不适用

The Role of Sox2 in Tumor Genesis and Migration in Colorectal Cancer

Sun Yat-sen University0 个研究点目标入组 136 人开始时间: 2005年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
136

研究概览

简要总结

Sox2 has been studied in several types of human solid tumors. The investigators found that Sox2 had higher expression level in colorectal cancer and metastatic tissues than normal tissues. So the investigators assumed that whether Sox2 plays an important role in the progression and migration of colon cancer.

详细描述

In our study, we examined Sox2 expression in archived human colon cancer tissues and found that its Sox2 expression correlates with reduced patient survival, increased tumor grade and metastasis probability.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
24 Years 至 79 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Clinical diagnosis of colorectal cancer

排除标准

  • Clinical diagnosis characteristics not exactly described in the patients information

研究者

发起方
Sun Yat-sen University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Lixiao Xu

Laboratory of Cancer and Stem Cell Biology

Sun Yat-sen University

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