Identification the Expression of Sox2 in Colorectal Cancer Tissues

Completed

• Conditions: Colorectal Cancer

• Registration Number: NCT01589900
• Lead Sponsor: Sun Yat-sen University

Brief Summary

Sox2 has been studied in several types of human solid tumors. The investigators found that Sox2 had higher expression level in colorectal cancer and metastatic tissues than normal tissues. So the investigators assumed that whether Sox2 plays an important role in the progression and migration of colon cancer.

Detailed Description

In our study, we examined Sox2 expression in archived human colon cancer tissues and found that its Sox2 expression correlates with reduced patient survival, increased tumor grade and metastasis probability.

Study Timeline

• Study Start: 2005-01
• Primary Completion: 2006-12
• Study Completion: 2012-03
• Study First Submitted: 2012-04-30
• Status Verified: 2012-05
• Study First Submitted QC: 2012-05-01
• Study First Posted: 2012-05-02
• Last Update Submitted: 2012-05-02
• Last Update Posted: 2012-05-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 136

Inclusion Criteria

• Clinical diagnosis of colorectal cancer

Exclusion Criteria

• Clinical diagnosis characteristics not exactly described in the patients information

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified