Effectiveness of Medical Management of Fibrous Dysplasia of Bone.

Completed

• Conditions: Fibrous Dysplasia of Bone; McCune Albright Syndrome
• Interventions: Other: Evaluation and analysis of clinical data

• Registration Number: NCT05422833
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

The objective of our study was to assess the effectiveness of our reference center since its constitution.

In a retrospective cohort study, we compared the activity of our center, including the time elapsed between diagnosis and access to the center and the diagnostic delay of patients with fibrous dysplasia between two periods, 1996-2006 (before certification of our center) and 2007-2019 (after certification of our center).

Detailed Description

Not available

Study Timeline

• Study Start: 1996-01
• Primary Completion: 2019-12
• Study Completion: 2019-12
• Study First Submitted: 2022-05-10
• Status Verified: 2022-06
• Study First Submitted QC: 2022-06-16
• Last Update Submitted: 2022-06-16
• Study First Posted: 2022-06-21
• Last Update Posted: 2022-06-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 528

Inclusion Criteria

We have included children and adults with FD/MAS who visited at least once in our center (outpatient and hospitalized patients). The diagnosis was established by an expert of the center, based on clinical, biological, imaging and/or histological arguments

Exclusion Criteria

The absence of detectable bone lesion

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Before	Evaluation and analysis of clinical data	Children and adults with FD/MAS who visited at least once in our center (outpatient and hospitalized patients). and with the first visit in the center included between 1996 and 2006 - before certification of our center.
After	Evaluation and analysis of clinical data	Children and adults with FD/MAS who visited at least once in our center (outpatient and hospitalized patients). and with the first visit in the center included between 2007 and 2019 - after certification of our center.

Primary Outcome Measures

Name	Time	Method
to compare time elapsed between first symptomes or discovery of bone lesions and the diagnosis of FD	1996-2019	The main objective was to compare time elapsed between first symptomes or discovery of bone lesions and the diagnosis of FD, over 2 periods of time: 1996-2006 (before certification) and 2007-2019 (after certification).

Trial Locations

Locations (1)

rheumatology department, hopital Edouard Herriot; 🇫🇷 Lyon, France