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临床试验/JPRN-UMIN000041794
JPRN-UMIN000041794已完成未知

A multicenter, open-label, interventional study to verify for association between cognitive decline and olfactory disturbance using a DEmentia Screening Kit in subjects with normal cognitive function, mild cognitive impairment, and Alzheimer s dementia - DESK Study

Kobayashi Pharmaceutical Co., Ltd.0 个研究点目标入组 220 人开始时间: 2020年9月15日最近更新:
适应症

试验速览

阶段
未知
状态
已完成
入组人数
220

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
40years-old 至 90years-old(—)
性别
All

入选标准

  • 未提供

排除标准

  • Subjects who meet any of the exclusion criteria will not be enrolled in this study. 1) Subjects who have had an allergic reaction to a fragrance in the past. 2) Pregnant women or subjects who wish to become pregnant. 3) Subjects diagnosed with an olfactory disorder with a definite cause. 4) Subjects with epilepsy or who have a history of epilepsy. 5) Subjects with depression and other psychiatric disorders or who have a history of those. 6) Subjects who have taken a test such as MMSE or MoCA-J within one month of the date of obtaining consent. 7) Subjects who are expected to have a significant effect on the following olfactory functions. - Subjects who reported smoking on the day of the olfactometry. - Subjects who reported on the day of the olfactometry that they were concerned about olfactory dysfunction such as hay fever, rhinitis, or chronic sinusitis. - Subjects who reported using the perfume on the day of the olfactometry. - Subjects who reported consuming strongly smelling food from the day before to the day of the olfactometry. 8) Subjects who are bedridden or unconscious and determined to have severe Alzheimer's disease. 9) Current smoker. 10) Subjects who have been judged by the principal investigator or sub-investigator to be inappropriate for this study, in addition to the reasons listed above.

研究者

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