A Clinical study to evaluate the effect of local ayurvedic application in the treatment of infected wound.

Phase 2/3

Not yet recruiting

Conditions: Local infection of the skin and subcutaneous tissue, unspecified. Ayurveda Condition: DUSHTAVRANAH,

Registration Number: CTRI/2022/12/048541

Lead Sponsor: Tilak Ayurved Mahavidyalaya, Pune

Brief Summary: Today wound is basic problem in surgical practice Surgeon deals with inflammation & problem in healing in any surgical disorder. Even though Vrana is a natural process of healing it should be protected from dosha dushti from various microorganism, which may affect the vrana and delay the normal healing process. Wound has different aspect for healing process If is left untreated can leads to complication. So we are looking for effective management. Dushta Vrana (Infected wound) is a common problem faced in surgical practice. The presence of Dushta Vrana worsens the condition of the patient with different complicationsand maybecome fatal. Wound healingisanatural process, but factors like slough, infection and foreign bodies, affect the normal process of healing. A healthy wound in anormal body heals earlier with a minimum scar as compared to a contaminated wound. Therefore in the present concept, all efforts are directed to keep the wound clean during the various stages of its healing process. Wound is a physical injury to any of the tissues in the body that results in a break in the continuity of soft parts of body structures[8]. A process of healing of wound is a normal biological response to the injury that occurs naturally, as long as the local care is adequate. The normal phases of wound healing-reaction, regeneration, and remodeling take place without any difficulty, if wound is debrided properly of non-viable tissue and repaired it in a physiological manner. Acharya Sushruta has given much emphasis on Vaikruthapaham. Hence good wound healing with minimal or no scar formation is the prime motto.Sushruta, Charaka, Vaghbhata, Madhavakar and Sharangdhara have clearly mentioned that the Lakshanas of Dushta Vrana as foul smelling, continuously flowing pus discharge along with blood filled cavities, which can be correlated to non-healing or contaminated wound. Infected wounds mostly require surgical debridement to stabilize the patient as well as to promote healing process, longer hospitalization, and surgery with use of anaesthesia drug, wound care and also other expenses. MADHUYUKTA SHARPUNKHA CHOORNA LEP has property of non surgical debridement, less painful and economical. Hence it can be most affordable and convenient non surgical treatment.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 68

Inclusion Criteria

1. Patients having Dusta Vrana (infected Wound) irrespective of sex, age, occupation including surgical wounds 2) OPD & IPD patients from Shalya department of affiliated hospital 3) Dusta Vrana having dimension from 1 cm to 6 cm 4) Patients ready to give written consent will be selected. 5) Patients suffering from dushtavrana and lakshana like- Raga (redness).
Utsannamamsa (pale granulation tissue).
Vedanayukta(painful).
Dustastrava(discharge).
Dustagandhi(foul smelling).

Exclusion Criteria

Known case of -1) Osteomyelitis, Venous, Tubercular, Ischemic, Tropical, Neurogenic, malignant ulcers.2) Ulcers with gangrenous changes.
1. Patient is suffering from HIV.
1. Wound size more than 6 cm.
5)Diabetic wound.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Darshan Paariksha- Akruti,Vrana strava,Vrana Tala,Vranagandha	Baseline,1st, 3rd,5th,7th 10th Day
Saparshan pariksha-Sparshatva,local temperature	Baseline,1st, 3rd,5th,7th 10th Day
Prashn Pariksha- Daha,Vedna, kandu	Baseline,1st, 3rd,5th,7th 10th Day

Secondary Outcome Measures

Name	Time	Method
Recurrance of Akruti,Vrana strava,Vrana Tala,Vranagandha	,Sparshatva,local temperature,Daha,Vedna, kandu

Trial Locations

Locations (1): Tilak Ayurved Mahavidyalaya and Seth Tarachand Ramnath Charitable Ayurved Hospital
🇮🇳
Pune, MAHARASHTRA, India
Tilak Ayurved Mahavidyalaya and Seth Tarachand Ramnath Charitable Ayurved Hospital
🇮🇳Pune, MAHARASHTRA, India
DrSagar Dattatray Kathole
Principal investigator
7350984369
sagarkathole3@gmail.com